公开(公告)号：EP2540222A2

公开(公告)日：2013-01-02

申请号：EP11747749.7

申请日：2011-02-25

申请人： Knu-Industry Cooperation Foundation

发明人： SHIM, Eun Bo ,  LIM, Ki Moo

IPC分类号： A61B5/0464 ,  A61B5/04

CPC分类号： A61B5/107 ,  A61B5/02405 ,  A61B5/04012 ,  A61B5/0452 ,  A61B5/046 ,  A61B5/0464 ,  A61B5/1073 ,  A61B5/1075 ,  A61B5/7275 ,  A61B6/503 ,  A61B8/5223

摘要： Disclosed is an arrhythmia diagnosing method and device for diagnosing arrhythmia such as fibrillation or tachycardia. The arrhythmia diagnosing method includes the steps of: (a) measuring a heart dimension; (b) measuring a frequency of a cardiac electric wave; (c) measuring a conduction velocity of the cardiac electric wave; and (d) determining occurrence or absence of arrhythmia using the heart dimension, the frequency of the cardiac electric wave and the conduction velocity of the cardiac electric wave measured in steps (a), (b) and (c). With the present invention, it is possible to predict and diagnose an electric wave tornado, one of causes of arrhythmia, through the use of a non-dimensional parameter, to find out patents who may possibly be died of arrhythmia or may possibly come to brain death due to arrhythmia and to significantly reduce the mortality rate of patients who suffer from arrhythmia.

摘要翻译： 公开了用于诊断心律失常如心律失常或心动过速的心律失常诊断方法和装置。 心律失常诊断方法包括以下步骤：（a）测量心脏尺寸; （b）测量心电波的频率; （c）测量心脏电波的传导速度; 和（d）使用心脏尺寸，心脏电波的频率和在步骤（a），（b）和（c）中测量的心脏电波的传导速度来确定心律不齐的发生或不存在。 利用本发明，可以通过使用无量纲参数来预测和诊断电波龙卷风（心律不齐的原因之一），以找出可能因心律失常而死亡或可能进入脑部的专利 由于心律失常导致死亡，并显着降低患有心律失常的患者的死亡率。

公开(公告)号：EP3188059B1

公开(公告)日：2020-05-13

申请号：EP15835538.8

申请日：2015-08-31

申请人： KNU-Industry Cooperation Foundation

发明人： SHIM, Eun Bo

IPC分类号： G16H50/50 ,  G16H30/40 ,  A61B5/02

公开(公告)号：EP3188059A1

公开(公告)日：2017-07-05

申请号：EP15835538.8

申请日：2015-08-31

申请人： KNU-Industry Cooperation Foundation

发明人： SHIM, Eun Bo

IPC分类号： G06F19/00 ,  A61B5/02 ,  G06Q50/22

摘要： The present invention relates to a method for determining patient-specific blood vessel information. More specifically, the present invention relates to a method for determining patient-specific cardiovascular information by applying a simplified coronary circulation model thereto. Furthermore, the present invention relates to a method for determining a blood flow rate for branches of a blood vessel having originated from an artery of each patient. According to the present invention, the method for determining cardiovascular information by using a computer system comprises the steps of: receiving image data including a plurality of coronary arteries having originated from the aorta; processing the image data so as to generate a three-dimensional shape model of the plurality of coronary arteries; simulating a blood flow for the generated three-dimensional shape model of the plurality of coronary arteries; and determining a fractional flow reserve (FFR) of the respective coronary arteries with the blood flow simulation result. In the blood flow simulation step for the three-dimensional shape model of the plurality of coronary arteries, a computational fluid dynamics model is applied to the three-dimensional shape model of the coronary arteries, and a centralized parameter model to be combined with the computational fluid dynamics model uses a simplified coronary circulation model including coronary arteries, capillaries of the coronary arteries, and coronary veins.

摘要翻译： 本发明涉及一种用于确定患者特异性血管信息的方法。 更具体地，本发明涉及一种通过向其应用简化的冠状动脉循环模型来确定患者特异性心血管信息的方法。 此外，本发明涉及一种用于确定源自每个患者的动脉的血管的分支的血流速率的方法。 根据本发明，通过使用计算机系统确定心血管信息的方法包括以下步骤：接收包括源自主动脉的多个冠状动脉的图像数据; 处理图像数据以便生成多个冠状动脉的三维形状模型; 为所生成的多个冠状动脉的三维形状模型模拟血流; 并用血流模拟结果确定各个冠状动脉的分数血流储备（FFR）。 在用于多个冠状动脉的三维形状模型的血流模拟步骤中，将计算流体动力学模型应用于冠状动脉的三维形状模型，并将集中参数模型与计算 流体动力学模型使用简化的冠状动脉循环模型，包括冠状动脉，冠状动脉的毛细血管和冠状静脉。