专利检索 ap:("KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY" OR "KOREA GREEN CROSS CORPORATION") AND inv:"HONG, Hyo, Jeong" 第 1 页

1.

发明授权
HUMANIZED ANTIBODY SPECIFIC FOR SURFACE ANTIGEN PRE-S1 OF HBV AND PREPARATION METHOD THEREOF 有权
标题翻译：专门为乙肝表面抗原前S1及其制备人源化抗体

公开(公告)号：EP1131358B1

公开(公告)日：2004-12-22

申请号：EP99972646.6

申请日：1999-11-19

申请人： KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY , KOREA GREEN CROSS CORPORATION

发明人： HONG, Hyo, Jeong , RYU, Chun, Jeih , HUR, Hyangsuk

IPC分类号： C07K16/28 , C12N15/13 , C12N15/63 , A61K39/395

CPC分类号： C07K16/082 , C07K2317/24 , C07K2317/56 , C07K2317/92

2.

发明公开
HUMANIZED ANTIBODY SPECIFIC FOR SURFACE ANTIGEN PRE-S1 OF HBV AND PREPARATION METHOD THEREOF 有权
标题翻译：专门为乙肝表面抗原前S1及其制备人源化抗体

公开(公告)号：EP1131358A1

公开(公告)日：2001-09-12

申请号：EP99972646.6

申请日：1999-11-19

申请人： KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY , KOREA GREEN CROSS CORPORATION

发明人： HONG, Hyo, Jeong , RYU, Chun, Jeih , HUR, Hyangsuk

IPC分类号： C07K16/28 , C12N15/13 , C12N15/63 , A61K39/395

CPC分类号： C07K16/082 , C07K2317/24 , C07K2317/56 , C07K2317/92

摘要： The present invention relates to humanized antibodies specific for HBV surface antigen pre-S1, which show binding affinity similar to mouse monoclonal antibody and which show remarkably reduced immunogenicity since they have less mouse-derived amino acid residues. Thus, the humanized antibodies of the present invention may be useful for the prevention of HBV infection and for the treatment of hepatitis B.