公开(公告)号：EP1570847A4

公开(公告)日：2008-10-08

申请号：EP03812356

申请日：2003-12-01

申请人： KYORIN SEIYAKU KK

发明人： NAGASAWA MICHIAKI ,  MACKENZIE SIMON JOHN

IPC分类号： A61K31/437 ,  A61P25/14 ,  A61P25/16 ,  A61P25/28 ,  A61P43/00 ,  A61P25/18

CPC分类号： A61K31/437

摘要： It is intended to provide PDE10A inhibitors which are useful in preventing or treating Parkinson's disease, Huntington's disease, Alzheimer's disease or integration dysfunction syndrome. A phosphodiesterase 10A inhibitor characterized by containing, as the active ingredient, a pyrazolo[1,5-a]pyridine derivative represented by the following general formula (1) is useful in preventing or treating Parkinson's disease, Huntington's disease, Alzheimer's disease or integration dysfunction syndrome: (1) wherein R and R independently represent each hydrogen or C1-4 lower alkyl; and R represents hydrogen, C1-4 lower alkyl or C1-3 lower alkoxy.