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1.发明授权Method for producing L-histidine by fermentation using aminoquinoline resistant bacterial strains of the genus Escherichia 有权一种用于通过埃希氏菌属的细菌的抗性氨基喹啉菌株发酵生产L-组氨酸的方法
公开(公告)号：EP1085087B1
公开(公告)日：2007-06-20
申请号：EP00120126.8
申请日：2000-09-19
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2.发明公开Method for producing amino acids by fermentation using DNA gyrase inhibitor resistant bacterial strains 有权维生素Zur发酵法Herstellung von L-Histidin durch DNA-gyraseinhibitor-resistenteBakterienstämme
公开(公告)号：EP1085086A2
公开(公告)日：2001-03-21
申请号：EP00120125.0
申请日：2000-09-19
CPC分类号： C12P13/24 , C12P13/04 , C12R1/19 , Y10S435/83 , Y10S435/832 , Y10S435/839 , Y10S435/843 , Y10S435/849 , Y10S435/88 , Y10S435/881
摘要： The present invention provides an industrially efficient method for producing an L-amino acid useful as medicament, chemical agent, food material and feed additive, and the method comprising culturing in a medium a microorganism having an ability to produce the L-amino acid and having resistance to a DNA gyrase inhibitor or a microorganism having an ability to produce the L-amino acid and having both resistance to a DNA gyrase inhibitor and resistance to an aminoquinoline derivative, producing and accumulating the L-amino acid therein and recovering the L-amino acid therefrom.
摘要翻译： 本发明提供了用于制备可用作药物，化学试剂，食品材料和饲料添加剂的L-氨基酸的工业上有效的方法，所述方法包括在培养基中培养具有产生L-氨基酸的能力的微生物并具有 对DNA促旋酶抑制剂或具有产生L-氨基酸的能力并对DNA促旋酶抑制剂具有抗性和对氨基喹啉衍生物具有抗性的微生物的抗性，其中产生和积累L-氨基酸并回收L-氨基酸 酸。
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3.发明授权Method for producing L-histidine by fermentation using DNA gyrase inhibitor resistant bacterial strains 有权一种用于通过细菌DNA促旋酶抑制剂抗性的菌株发酵生产L-组氨酸的方法
公开(公告)号：EP1085086B1
公开(公告)日：2008-03-19
申请号：EP00120125.0
申请日：2000-09-19
CPC分类号： C12P13/24 , C12P13/04 , C12R1/19 , Y10S435/83 , Y10S435/832 , Y10S435/839 , Y10S435/843 , Y10S435/849 , Y10S435/88 , Y10S435/881
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4.发明公开Method for producing amino acids by fermentation using aminoquinoline resistant bacterial strains 有权Verfahren zur fermentativen Herstellung von L-Histidin durch Aminochinolin-resistenteBakterienstämmeder Gattung Escherichia
公开(公告)号：EP1085087A2
公开(公告)日：2001-03-21
申请号：EP00120126.8
申请日：2000-09-19
摘要： The present invention provides a method for producing an amino acid selected from the group consisting of L-alanine, L-valine, L-leucine, L-isoleucine, L-methionine, L-phenylalanine, L-proline, glycine, L-serine, L-threonine, L-cysteine, L-tyrosine, L-asparagine, L-glutamine, L-lysine, L-histidine, L-arginine, L-aspartic acid and L-glutamic acid and useful as medicament, chemical agent, food material and feed additive at high industrial efficiency, the method comprising culturing a microorganism having an ability to produce the amino acid and having resistance to an aminoquinoline derivative in a medium, producing and accumulating the amino acid in the present invention in the culture, and recovering the amino acid from the culture.
摘要翻译： 本发明提供了选自L-丙氨酸，L-缬氨酸，L-亮氨酸，L-异亮氨酸，L-甲硫氨酸，L-苯丙氨酸，L-脯氨酸，甘氨酸，L-丝氨酸的氨基酸的制备方法 ，L-苏氨酸，L-半胱氨酸，L-酪氨酸，L-天冬酰胺，L-谷氨酰胺，L-赖氨酸，L-组氨酸，L-精氨酸，L-天冬氨酸和L-谷氨酸，可用作药物， 食品原料和饲料添加剂，该方法包括在培养基中培养具有产生氨基酸并具有对氨基喹啉衍生物的抗性的微生物，在培养物中产生和积累本发明中的氨基酸，以及 从培养物中回收氨基酸。
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