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    Process for producing L-phenylalanine
    4.
    发明公开
    Process for producing L-phenylalanine 失效
    Verfahren zur Herstellung von L-Phenylalanin。

    公开(公告)号：EP0395124A1

    公开(公告)日：1990-10-31

    申请号：EP90111662.4

    申请日：1985-02-07

    申请人： KYOWA HAKKO KOGYO CO., LTD

    发明人： Araki, Kazumi ,  Ozeki, Toshitsugu ,  Ito, Yukiyoshi ,  Ishino, Shuichi ,  Anazawa, Hideharu ,  Kamimori, Shigeru

    IPC分类号： C12P13/22

    CPC分类号： C12P13/222 ,  Y10S435/822 ,  Y10S435/83 ,  Y10S435/832 ,  Y10S435/843 ,  Y10S435/847 ,  Y10S435/85 ,  Y10S435/852 ,  Y10S435/859 ,  Y10S435/873 ,  Y10S435/877 ,  Y10S435/879 ,  Y10S435/881

    摘要： A process for producing L-phenylalanine is carried out by culturing a micro­organism belonging to the genus Serratia , Escherichia , Pseudomonas , Enterobacter , Salmonella , Erwinia , Proteus , Citrobacter , Paracoccus , Arthriobacter , Bacillus , Brevi­bacterium , Corynebacterium , Flavobacterium , Klebsiella , Kluyvera or Micrococcus having the ability to convert phenypyruvic acid into L-phenylalanine in the presence of fumaric acid and ammonium ion or urea, in a culture medium containing phenylpyruvic acid, fumaric acid and ammonium ion or urea or causing cells of said microorganism or product of treatment thereof to react on phenylpyruvic acid, fumaric acid and ammonium ion or urea in an aqueous solution; forming L-phenylalanine in the resultant culture broth or aqueous solution; and recovering L-phenylalanine therefrom.

    摘要翻译： 生产L-苯丙氨酸的方法是通过培养属于沙雷氏菌属，大肠杆菌属，假单胞菌属，肠杆菌属，沙门氏菌属，欧文氏菌属，变形杆菌属，柠檬酸杆菌属，副球菌属，杆状杆菌属，芽孢杆菌属，短杆菌属，棒状杆菌属，黄杆菌属，克雷伯杆菌属，克鲁维酵母属或 在含有苯丙酮酸，富马酸和铵离子或尿素的培养基中，在富马酸和铵离子或尿素存在下，将苯丙氨酸转化为L-苯丙氨酸的能力的微球菌，或引起所述微生物的细胞或其处理产物 在水溶液中与苯基丙酮酸，富马酸和铵离子或脲反应; 在所得培养液或水溶液中形成L-苯丙氨酸; 并从中回收L-苯丙氨酸。

    Process for producing L-phenylalanine
    7.
    发明公开
    Process for producing L-phenylalanine 失效
    Verfahren zur Herstellung von L-Phenylalanin。

    公开(公告)号：EP0151488A2

    公开(公告)日：1985-08-14

    申请号：EP85101298.9

    申请日：1985-02-07

    申请人： KYOWA HAKKO KOGYO CO., LTD.

    发明人： Araki, Kazumi ,  Ozeki, Toshitsugu ,  Ito, Yukiyoshi ,  Ishino, Shuichi ,  Anazawa, Hideharu ,  Kamimori, Shigeru

    IPC分类号： C12P13/22 ,  C12N1/20

    CPC分类号： C12P13/222 ,  Y10S435/822 ,  Y10S435/83 ,  Y10S435/832 ,  Y10S435/843 ,  Y10S435/847 ,  Y10S435/85 ,  Y10S435/852 ,  Y10S435/859 ,  Y10S435/873 ,  Y10S435/877 ,  Y10S435/879 ,  Y10S435/881

    摘要： A process for producing L-phenylalanine is carried out by (1) culturing a microorganism belonging to the genus Citrobacter, Erwinia, Enterobacter, Klebsiella, Microbacterium, Salmonella, Bacillus, Corynebacterium or Flavobacterium having the ability to convert phenylpyruvic acid into L-phenylalanine in the presence of an amino group donor, in a culture medium containing phenylpyruvic acid and an amino group donor or causing cells of the microorganism or product of treatment thereof to react on phenylpyruvic acid and an amino group donor in an aqueous solution; or by (2) culturing a microorganism belonging to the genus Serratia, Escherichia, Pseudomonas, Enterobacter, Salmonella, Erwinia, Proteus, Citrobacter, Paracoccus, Arthrobacter, Bacillus, Brevibacterium, Corynebacterium, Flavobacterium, Klebsiella, Kluyvera or Micrococcus having the ability to convert phenypyruvic acid into L-phenylalanine in the presence of fumaric acid and ammonium ion or urea, in a culture medium containing phenylpyruvic acid, fumaric acid and ammonium ion or urea or causing cells of said microorganism or product of treatment thereof to react on phenylpyruvic acid, fumaric acid and ammonium ion or urea in an aqueous solution; forming L-phenylalanine in the resultant culture broth or aqueous solution; and recovering L-phenylalanine therefrom.

    摘要翻译： 通过（1）将苯丙酮酸转化为L-苯丙氨酸的能力培养属于柠檬酸杆菌属，欧文氏菌属，肠杆菌属，克雷伯杆菌属，微杆菌属，沙门氏菌属，芽孢杆菌属，棒杆菌属或黄杆菌属的微生物，进行L-苯丙氨酸生产的方法 在含有苯丙酮酸和氨基供体的培养基中，氨基供体的存在或使微生物的细胞或其处理产物在水溶液中与苯基丙酮酸和氨基供体反应; 或通过（2）具有转化能力的沙雷氏菌属，埃希氏杆菌属，假单胞菌属，肠杆菌属，沙门氏菌属，欧文氏菌属，变形杆菌属，柠檬酸杆菌属，副球菌属，节杆菌属，芽孢杆菌属，短杆菌属，棒状杆菌属，黄杆菌属，克雷伯菌属，克鲁维酵母属或微球菌属的微生物 在含有苯基丙酮酸，富马酸和铵离子或尿素的培养基中，在富马酸和铵离子或尿素的存在下，将苯丙氨酸转化成L-苯丙氨酸，或使所述微生物的细胞或其处理产物与苯基丙酮酸反应， 富马酸和铵离子或尿素在水溶液中; 在所得培养液或水溶液中形成L-苯丙氨酸; 并从中回收L-苯丙氨酸。