公开(公告)号：EP0587182B1

公开(公告)日：1999-12-15

申请号：EP93114582.5

申请日：1993-09-10

申请人： KYOWA HAKKO KOGYO KABUSHIKI KAISHA

发明人： Yokomori, Yorozu ,  Murayama, Toshikazu ,  Masada, Tomoaki ,  Ohta, Motohiro ,  Azuma, Masaki ,  Yumiba, Yoshio

IPC分类号： A23K1/16 ,  A23K1/18

CPC分类号： A61K9/5036 ,  A23K40/35 ,  A61K9/501 ,  A61K9/5015 ,  A61K9/5026 ,  A61K9/5042 ,  A61K9/5047

公开(公告)号：EP0587182A3

公开(公告)日：1995-02-15

申请号：EP93114582.5

申请日：1993-09-10

申请人： KYOWA HAKKO KOGYO KABUSHIKI KAISHA

发明人： Yokomori, Yorozu ,  Murayama, Toshikazu ,  Masada, Tomoaki ,  Ohta, Motohiro ,  Azuma, Masaki ,  Yumiba, Yoshio

IPC分类号： A23K1/16 ,  A23K1/18

CPC分类号： A61K9/5036 ,  A23K40/35 ,  A61K9/501 ,  A61K9/5015 ,  A61K9/5026 ,  A61K9/5042 ,  A61K9/5047

摘要： Disclosed is a process for producing a composition for ruminants, which is characterized in that a nucleus containing a physiologically active substance is coated with a coating material prepared by suspending in water (i) an emulsion comprising water and at least one hydrophobic substance hardly soluble in water and (ii) a slurry containing at least one polymer soluble in water of pH 5.0 or below and insoluble in water of pH over 5.0 In the process, an aqueous suspension is used for coating instead of a meterial dissolved in an organic solvent.

公开(公告)号：EP0587182A2

公开(公告)日：1994-03-16

申请号：EP93114582.5

申请日：1993-09-10

申请人： KYOWA HAKKO KOGYO KABUSHIKI KAISHA

发明人： Yokomori, Yorozu ,  Murayama, Toshikazu ,  Masada, Tomoaki ,  Ohta, Motohiro ,  Azuma, Masaki ,  Yumiba, Yoshio

IPC分类号： A23K1/16 ,  A23K1/18

CPC分类号： A61K9/5036 ,  A23K40/35 ,  A61K9/501 ,  A61K9/5015 ,  A61K9/5026 ,  A61K9/5042 ,  A61K9/5047

摘要： Disclosed is a process for producing a composition for ruminants, which is characterized in that a nucleus containing a physiologically active substance is coated with a coating material prepared by suspending in water (i) an emulsion comprising water and at least one hydrophobic substance hardly soluble in water and (ii) a slurry containing at least one polymer soluble in water of pH 5.0 or below and insoluble in water of pH over 5.0
In the process, an aqueous suspension is used for coating instead of a meterial dissolved in an organic solvent.

摘要翻译： 本发明公开了一种反刍动物组合物的制造方法，其特征在于，含有生理活性物质的细胞核涂覆有通过在水中悬浮制备的涂料（i）包含水和至少一种难溶于 水和（ii）含有至少一种可溶于pH 5.0或以下的水的聚合物并且不溶于pH超过5.0的水的浆料。在该方法中，使用水性悬浮液代替溶解在有机溶剂中的水溶液。