公开(公告)号：EP2025354A1

公开(公告)日：2009-02-18

申请号：EP07743205.2

申请日：2007-05-11

申请人： Keio University ,  Meiji Seika Kaisha Ltd.

发明人： IZUMI, Yotaro ,  KAWAMURA, Masafumi ,  KOBAYASHI, Koichi ,  ENDO, Takeshi ,  NAGAI, Atsushi ,  SHICHINOHE, Makoto

IPC分类号： A61L31/00 ,  A61K31/785 ,  A61P7/04 ,  A61P41/00

CPC分类号： A61K31/785 ,  A61L31/06 ,  C08L77/04

摘要： There is disclosed an organ-adhesion preventing agent comprising a chemically-crosslinked γ-polyglutamic acid as an effective ingredient, as well as a process for preventing organ from adhesion comprising a step of bringing the adhesion-preventing agent into contact with or depositing the same onto the surface of a local organ and optionally the neighborhood thereof to be prevented from the post-operative adhesion. According to the present invention, there is provided an adhesion-preventing agent which is capable of effectively preventing the surfaces of organs from adhesion, and which can be absorbed in the body with high safety and be produced with ease and has high practical usefulness, as well as a process for preventing organ from adhesion by using the adhesion-preventing agent.

摘要翻译： 公开了一种包含化学交联的3-聚谷氨酸作为有效成分的器官粘附防止剂，以及防止器官粘连的方法，包括使粘附防止剂与其接触或沉积的步骤 到局部器官的表面上，并且可选地，其附近被防止术后粘连。 根据本发明，提供了一种能够有效地防止器官表面粘附的粘合防止剂，其能够以高安全性被吸收在身体中并且易于制造并且具有高实用性，如 以及通过使用防粘连剂防止器官粘连的方法。