公开(公告)号：EP2020445B1

公开(公告)日：2013-01-02

申请号：EP06746349.7

申请日：2006-05-12

申请人： Keio University ,  Oriental Yeast Co., Ltd.

发明人： MARUYAMA, Kenta ,  MATSUO, Koichi, c/o Keio University ,  YASUDA, Hisataka, c/o Oriental Yeast Co., Ltd.

IPC分类号： C12Q1/00 ,  A61K38/00 ,  A61P31/00 ,  A61P37/00 ,  C07K16/28 ,  C12N15/09 ,  C12Q1/68 ,  G01N33/483 ,  G01N33/53

CPC分类号： G01N33/566 ,  A61K38/191 ,  A61K38/193 ,  C12Q1/6883 ,  C12Q2600/158 ,  G01N2333/70575 ,  G01N2800/26 ,  Y02A50/481 ,  A61K2300/00

摘要： A novel method for detection of an inflammatory disease and a novel composition for prevention or treatment of an inflammatory disease are provided. The method for detection of an inflammatory disease comprises using RANKL and/or OPG as a marker in a biological sample. The composition for prevention or treatment of an inflammatory disease comprises RANKL and/or M-CSF as an active ingredient.

公开(公告)号：EP2020445A1

公开(公告)日：2009-02-04

申请号：EP06746349.7

申请日：2006-05-12

申请人： Keio University ,  Oriental Yeast Co., Ltd.

发明人： MARUYAMA, Kenta, c/o Keio University ,  MATSUO, Koichi, c/o Keio University ,  YASUDA, Hisataka, c/o Oriental Yeast Co., Ltd.

IPC分类号： C12Q1/00 ,  A61K38/00 ,  A61P31/00 ,  A61P37/00 ,  C07K16/28 ,  C12N15/09 ,  C12Q1/68 ,  G01N33/483 ,  G01N33/53

CPC分类号： G01N33/566 ,  A61K38/191 ,  A61K38/193 ,  C12Q1/6883 ,  C12Q2600/158 ,  G01N2333/70575 ,  G01N2800/26 ,  Y02A50/481 ,  A61K2300/00

摘要： A novel method for detection of an inflammatory disease and a novel composition for prevention or treatment of an inflammatory disease are provided. The method for detection of an inflammatory disease comprises using RANKL and/or OPG as a marker in a biological sample. The composition for prevention or treatment of an inflammatory disease comprises RANKL and/or M-CSF as an active ingredient.

摘要翻译： 提供了用于检测炎性疾病以及用于预防或治疗炎性疾病的新型组合物的新方法。 检测炎性疾病的方法，包括使用RANKL和/或OPG作为生物样品中的标记物。 对于炎症性疾病的预防或治疗组合物包含RANKL和/或M-CSF作为活性成分。