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公开(公告)号：EP4308950A1
公开(公告)日：2024-01-24
申请号：EP22711248.9
申请日：2022-03-11
发明人： KEUPP, Jochen , MEINEKE, Jan Jakob , STEHNING, Christian , SCHÜLKE, Christophe Michael Jean , DONEVA, Mariya Ivanova , BÖRNERT, Peter Ulrich
IPC分类号： G01R33/563 , G01R33/48 , A61B5/055 , G01R33/56 , G01R33/567 , A61B5/00 , G01R33/561 , A61B5/024 , A61B5/08
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公开(公告)号：EP3497463A1
公开(公告)日：2019-06-19
申请号：EP17748472.2
申请日：2017-08-03
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公开(公告)号：EP4137834A1
公开(公告)日：2023-02-22
申请号：EP21191724.0
申请日：2021-08-17
发明人： BOERNERT, Peter , NEHRKE, Kay , AMTHOR, Thomas Erik , MEINEKE, Jan Jakob , BAUMANN, Manuel , MAZURKEWITZ, Peter Caesar , KEUPP, Jochen , DONEVA, Mariya Ivanova , VAN DEN BRINK, Johan Samuel
IPC分类号： G01R33/483 , G01R33/54 , G01R33/56 , G01R33/561 , G01R33/44 , G01R33/50 , G01R33/563
摘要： The invention relates to a method of MR imaging of an object (10) placed in an examination volume of an MR system (1). It is an object of the invention to provide an improved quantitative MR imaging technique. The method comprises the steps of: subjecting the object (10) to an imaging sequence which generates MR signals in two or more spatially separate slices or volumes, wherein the imaging sequence is composed of a train of sequence blocks, each sequence block comprising at least one RF pulse and at least one switched readout magnetic field gradient defining a k-space sampling pattern and having associated therewith a set of acquisition parameters, acquiring the MR signals, wherein the MR signals are generated and/or manipulated in only a subset of said slices or volumes during each sequence block to acquire the MR signals in a time-multiplexed manner from all of the slices or volumes while simultaneously varying at least one acquisition parameter during the course of the imaging sequence, and reconstructing at least one MR image for each slice or volume, wherein one or more MR parameters are computed for a number of image positions from the temporal evolution of the acquired MR signals caused by the variation of the at least one acquisition parameter. Moreover, the invention relates to an MR system (1) for carrying out this method as well as to a computer program to be run on an MR system.
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公开(公告)号：EP3391069A1
公开(公告)日：2018-10-24
申请号：EP16806191.9
申请日：2016-12-12
CPC分类号： G01R33/56 , G01R33/5608
摘要： The invention provides for a medical imaging system (100, 400) comprising: a memory (112) for storing machine executable instructions and a processor (106) for controlling the medical imaging system. Execution of the machine executable instructions cause the processor to: receive (200) a preliminary segmentation (124) from a preliminary magnetic resonance image (122) of a region of interest (409), wherein the preliminary segmentation comprises preliminary segmentation edges; reconstruct (202) a first QSM image (124) for the region of interest from QSM magnetic resonance data (122), wherein the reconstruction of the QSM image is at least partially performed using a regularization function, wherein the regularization function is dependent upon the preliminary segmentation edges during reconstruction of the first QSM image; calculate (204) a first segmentation (126) by segmenting the first QSM image using a QSM image segmentation algorithm (134), wherein the first segmentation comprises first segmentation edges; and reconstruct (206) a second QSM image (128) for the region of interest from the QSM magnetic resonance data, wherein the reconstruction of the second QSM image is at least partially performed using the regularization function, wherein the regularization function is dependent upon the first segmentation edges.
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公开(公告)号：EP4450994A1
公开(公告)日：2024-10-23
申请号：EP23168889.6
申请日：2023-04-20
摘要： Disclosed herein is a medical system (100, 300, 500) comprising a memory (116) storing machine executable instructions (120) and a graph database (122). The graph database is configured to output magnetic resonance imaging pulse sequence configuration data (126) in response to receiving subject data. The medical system further comprises a computational system (110). Execution of the machine executable instructions causes the computational system to: receive (200) the subject data; and receive (202) the magnetic resonance imaging pulse sequence configuration data in response to inputting the subject data into the graph database.
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公开(公告)号：EP4060362A1
公开(公告)日：2022-09-21
申请号：EP21163453.0
申请日：2021-03-18
发明人： KEUPP, Jochen , MEINEKE, Jan Jakob , STEHNING, Christian , SCHUELKE, Christophe Michael Jean , DONEVA, Mariya Ivanova , BOERNERT, Peter
IPC分类号： G01R33/48 , A61B5/055 , G01R33/56 , G01R33/563 , G01R33/567 , G01R33/561
摘要： Disclosed herein is a medical system (100, 300, 700) comprising a magnetic resonance imaging system (102) configured to acquire lines of k-space (144) data from a thoracic region (122) of a subject (118). Execution of machine executable instructions (140) causes a computational system (132) to: repeatedly (200) acquire the lines of k-space data by controlling the magnetic resonance imaging system with the pulse sequence commands; repeatedly (202) assemble motion resolved k-space data (146) from the lines of k-space data using at least one cardiac phase and one respiratory phase of the subject as the k-space data is acquired; retrieve (204) at least a portion (148) of the motion resolved k-space data during acquisition of the k-space data; and construct (206) a preliminary three-dimensional cardiac image (150) using at least a portion of the motion resolved k-space data before acquisition of the lines of k-space data is finished. The pulse sequence commands are according to a three-dimensional free running cardiac magnetic resonance imaging protocol.
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公开(公告)号：EP4361659A1
公开(公告)日：2024-05-01
申请号：EP22203550.3
申请日：2022-10-25
发明人： MEINEKE, Jan Jakob , NIELSEN, Tim
IPC分类号： G01R33/28 , G01R33/56 , G01R33/563
CPC分类号： G01R33/283 , G01R33/56325 , G01R33/5608 , G01R33/4835
摘要： Disclosed herein is a method comprising: controlling a magnetic resonance imaging system to acquire k-space data from a thoracic region of a subject in stacks of slices, each stack s having a respective orientation, wherein the k-space data is acquired in a set of frames per slice, each frame f having k-space data ys,f that is aquired during an acquisition time tf, each frame ys,t comprising k-space data ys,f,p of each cardiac phase p that is covered by the acquisition time tf; and processing the acquired data cardiac phase-wise for determining per cardiac phase p a three-dimensional, 3D, cardiac image that is motion corrected, the determination being performed by minimizing an error between image data representing xs,f,p the k-space data ys,f,p of a current cardiac phase p and a corresponding prediction x̂s,f,p that is obtained from an estimate Xp of a 3D cardiac image.
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公开(公告)号：EP3865892A1
公开(公告)日：2021-08-18
申请号：EP20157618.8
申请日：2020-02-17
发明人： NIELSEN, Tim , MEINEKE, Jan Jakob
IPC分类号： G01R33/565 , G01R33/56 , G01R33/561
摘要： Disclosed herein is a medical system (100, 300). The execution of machine executable instructions (120) causes a processor (104) to: receive (200) measured gradient echo k-space data (122); receive (202) an off-resonance phase map (124); reconstruct (204) an initial magnetization image (126) from the measured gradient echo k-space data; calculate (206) an upsampled phase map (128) from the off-resonance phase map; calculate (208) an upsampled magnetization image (130) from the initial magnetization image; calculating (210) a modulated image (132) by modulating the upsampled magnetization image with the upsampled phase map; calculate (212) a corrected image (134) comprising iteratively. The iterative calculation comprises: calculating (214) updated k-space data by applying a data consistency algorithm (138) to a k-space representation of the modulated image and the measured gradient echo k-space data and calculating (216) an updated image (142) from the updated k-space data. Calculation of the updated image comprises demodulation by the upsampled phase map and applying a smoothing algorithm.
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公开(公告)号：EP3742184A1
公开(公告)日：2020-11-25
申请号：EP19175293.0
申请日：2019-05-20
发明人： LEUSSLER, Christoph , FINDEKLEE, Christian , MEINEKE, Jan Jakob , VERNICKEL, Inventor , KOKEN, Peter
IPC分类号： G01R33/565 , G01R33/567 , A61B6/03 , G01R33/36 , G01S13/48
摘要： Disclosed is a medical system (100, 300, 500, 700) comprising: a memory (128) storing machine executable instructions (130); a processor (122) configured for controlling the medical system; and a pilot tone system (106). The pilot tone system comprises a radio frequency system (108) comprising multiple transmit channels (110) and multiple receive channels (112). The multiple transmit channels are configured for each transmitting unique pilot tone (132) signals via multiple transmit coils. The multiple receive channels are configured for receiving multi-channel pilot tone data (134) via multiple receive coils. Execution of the machine executable instructions causes the processor to: transmit (200) multi-channel pilot tone signals by controlling at least a portion of the multiple transmit channels to transmit the unique pilot tone signals; acquire (202) multi-channel pilot tone data (134) by controlling at least a portion of the multiple receive channels to receive the multi-channel pilot tone data; and determine (204) a motion state (136) of the subject using the multi-channel pilot tone data.
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10.发明公开
公开(公告)号：EP3696561A1
公开(公告)日：2020-08-19
申请号：EP19157075.3
申请日：2019-02-14
IPC分类号： G01R33/36 , G01R33/565
摘要： The invention relates to a system for detecting subject motion in magentic resonance imaging. It is proposed herein to increase the sensitivity of noise data to subject motion by changing the pre-amplifiers (3) operating point appropriately. A switchable impedance matching circuit (4) is placed in the RF receive chain (1), which allows adjustment of the load impedance presented to the pre-amplifier (3) by the RF coil (2, 9) to different operating points. In order to adjust the load impedance, the system proposed herein comprises a first impedance matching circuit (5), wherein the first impedance matching circuit (5) has an operating point that is optimized for an high Signal-to-Noise-Ratio. The switchable impedance matching circuit (4) further comprises a second impedance matching circuit (6), wherein the second impedance matching circuit (6) has an operating point that is optimized for high derivative noise figure with respect to the input impedance of the pre-amplifier. In contrast, the proposed switchable impedance matching circuit (4) is capable of adjusting the load impedance presented to the pre-amplifier (3) by the RF receive coil (2, 9) without the need for setting the operating point of a single impedance matching circuit from a minimal noise figure input impedance to a region where the absolute value derivative of the noise figure in terms of input impedance is maximal. The present invention further provides a magnetic resonance imaging system comprising a system for detecting subject motion in magnetic resonance imaging. The present invention further provides a method for detecting subject motion in magnetic resonance imaging, a computer program product for motion detection in magnetic resonance imaging and a computer readable medium containing program instructions for execution on a computer system.
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