公开(公告)号：EP4074315A1

公开(公告)日：2022-10-19

申请号：EP22176241.2

申请日：2019-04-23

申请人： Korea Institute of Radiological & Medical Sciences

发明人： LIM, Young Bin ,  PARK, Myung Jin ,  LEE, Hyoun Ji

IPC分类号： A61K31/546 ,  A61K31/4515 ,  A61K31/496 ,  A61P43/00 ,  A23L33/10 ,  A61K31/5415 ,  A61P35/00 ,  A61K45/06

摘要： The present invention relates to a composition for enhancing radiation sensitivity comprising aripiprazole as an active ingredient, and more specifically, to a composition for enhancing radiation sensitivity capable of treating cancer by acting as a radiation sensitizer when aripiprazole is combined with radiation. By administering an effective amount of aripiprazole according to the present invention in combination with radiation irradiation, it has excellent radiation sensitivity enhancing effects such as reducing cancer cell viability and inducing cancer cell death, so it can be usefully used as a radiation sensitivity enhancer.

公开(公告)号：EP3789029A1

公开(公告)日：2021-03-10

申请号：EP19796396.0

申请日：2019-04-23

申请人： Korea Institute of Radiological & Medical Sciences

发明人： LIM, Young Bin ,  PARK, Myung Jin ,  LEE, Hyoun Ji

IPC分类号： A61K31/546 ,  A61K31/4515 ,  A61K31/496 ,  A61P43/00 ,  A23L33/10 ,  A61K31/5415 ,  A61P35/00

摘要： The present invention relates to a composition for enhancing radiation sensitivity comprising aripiprazole as an active ingredient, and more specifically, to a composition for enhancing radiation sensitivity capable of treating cancer by acting as a radiation sensitizer when aripiprazole is combined with radiation. By administering an effective amount of aripiprazole according to the present invention in combination with radiation irradiation, it has excellent radiation sensitivity enhancing effects such as reducing cancer cell viability and inducing cancer cell death, so it can be usefully used as a radiation sensitivity enhancer.