公开(公告)号：EP4269429A1

公开(公告)日：2023-11-01

申请号：EP21911559.9

申请日：2021-12-22

申请人： Korea Institute of Science and Technology

发明人： JANG, Mi-Hue ,  YUK, Chae-Min ,  GO, Ga-Yeon ,  LEE, Young-Eun ,  SHIN, Sang-Chul

IPC分类号： C07K14/495 ,  C07K7/08 ,  C07K7/06 ,  A61K38/00 ,  A61P35/00

摘要： The present invention relates to a novel peptide capable of inhibiting TGF-β signaling and the use thereof. The peptide of the present invention is capable of inhibiting the TGF-β-induced signaling pathway or the expression of TGF-β, and thus can treat or prevent various diseases caused by TGF-β signaling, and furthermore, can effectively inhibit tumorigenesis processes such as TGF-β-signaling induced tumor growth and metastasis.