公开(公告)号：EP3831203A1

公开(公告)日：2021-06-09

申请号：EP19213224.9

申请日：2019-12-03

申请人： Seoul National University R & DB Foundation ,  Korea University Research and Business Foundation ,  Pukyong National University Industry- University Cooperation

发明人： AHN, Dong June ,  LEE, Ye Dam ,  KIM, Do Nyun ,  LEE, Chan Seok ,  WU, Sang Wook ,  PARK, Su Hyun

IPC分类号： A01N1/02

摘要： The present invention provides a composition for inhibiting ice recrystallization, including: A nucleic acid structure comprising a scaffold nucleic acid folded at predetermined positions to form a plurality of strands, and a plurality of staple nucleic acids, wherein at least a portion thereof has a complementary sequence to at least a portion of the scaffold nucleic acid, thereby binding to the scaffold nucleic acid to form a double strand. Therefore, it is possible to increase a survival rate of cells due to having excellent effect of inhibiting ice recrystallization upon cryopreservation of the cells, and maintain a texture of food even when using the composition in the freezing of food.

公开(公告)号：EP3808779A1

公开(公告)日：2021-04-21

申请号：EP19213193.6

申请日：2019-12-03

申请人： Korea University Research and Business Foundation

发明人： LEE, Seungwoo ,  AHN, Dong June ,  LIM, Dong Kwon ,  LEE, Jae Won ,  LEE, Sang Yup

IPC分类号： C07K17/14 ,  C12N1/04 ,  B82Y5/00 ,  A01N1/02

摘要： The present invention provides a a nanostructure which includes: a core comprising one or more planes configured to come into planar contact with at least one plane of an ice crystal; and an oligopeptide which is conjugated to at least one plane of the core and comprises (Thr) n -, (Ala) n -, (Ser) n -, or (Gly) n -, wherein the nanostructure is a polyhedron-shaped nanostructure present in water in a colloidal form to control freezing, and n is an integer of 2 to 7.

公开(公告)号：EP3239721A1

公开(公告)日：2017-11-01

申请号：EP15873421.0

申请日：2015-06-24

申请人： Korea University Research and Business Foundation

发明人： CHUNG, Seok ,  LEE, Eun Doo ,  YOON, Jung Hyo ,  HAN, Se Woon ,  KIM, Jae Ho ,  CHO, Young Kyu ,  LIM, David ,  JUNG, Yong Hun ,  AHN, Dong June

IPC分类号： G01P5/26

CPC分类号： G01P5/26 ,  B01L3/502746 ,  G01F1/708 ,  G01F1/7086 ,  G01P5/18 ,  G01S17/00

摘要： An apparatus for measuring fluid speed by using the refraction of light is disclosed. The apparatus includes: a channel in which a passage is formed to allow the flow of a fluid; a first and a second light source that are located in any one region of an upper part and a lower part of the channel; a sensor installed in an opposite region of the region where the first and second light sources are located with respect to the channel, to receive the light emitted from the first and second light sources; a speed calculation unit that calculates the speed of the fluid by using a time point at which the intensity of the light received at the sensor changes; and an adjustment unit that is connected to the channel and configured to adjust the flow speed of the fluid based on the calculated speed of the fluid.

摘要翻译： 公开了一种通过使用光的折射来测量流体速度的设备。 该设备包括：通道，其中形成通道以允许流体的流动; 第一光源和第二光源，位于所述通道的上部和下部的任意一个区域中; 传感器，其安装在第一光源和第二光源相对于通道所在的区域的相对区域中，以接收从第一光源和第二光源发射的光; 速度计算单元，其通过使用传感器处接收到的光的强度改变的时间点来计算流体的速度; 以及调整单元，其连接到所述通道并且被配置为基于计算出的流体的速度来调整流体的流速。

公开(公告)号：EP4256959A1

公开(公告)日：2023-10-11

申请号：EP21900742.4

申请日：2021-03-12

申请人： Korea University Research and Business Foundation ,  Seoul National University R & DB Foundation

发明人： AHN, Dong June ,  KIM, Do Nyun ,  LEE, Ye Dam ,  LEE, Chan Seok

IPC分类号： A01N1/02 ,  C07K7/06 ,  A23L3/3544 ,  A23L3/3526

摘要： The present invention relates to a composition for cryopreservation, comprising: a nucleic acid structure which comprises a scaffold nucleic acid folded at predetermined positions to form multiple strands, and a plurality of staple nucleic acids wherein at least a portion of a sequence thereof comprises a complementary sequence to that of the scaffold nucleic acid, which are bound to at least one of the strands of the scaffold nucleic acid to form a double strand; linkers coupled to at least one of single strands in the nucleic acid structure; and an anti-freezing peptide coupled to at least one of the linkers, so as to exhibit excellent freeze-protection effects, which in turn increase cell viability during cryopreservation of cells and tissues, while retaining original texture of food even when used for freezing the food.