EXOSOME-BASED NANOPARTICLE COMPOSITE AND METHOD FOR PREPARING SAME

    公开(公告)号:EP3583955A1

    公开(公告)日:2019-12-25

    申请号:EP18754947.2

    申请日:2018-02-02

    发明人: YUK, Soon Hong

    IPC分类号: A61K47/69 A61K47/10

    摘要: The present invention relates to an exosome-based nanoparticle composite and a method for preparing the same. More specifically, the present invention relates to an exosome-based nanoparticle composite that uses exosomes isolated from cells and a biocompatible polymer to achieve improved in vivo stability and redispersibility, and a method for preparing the nanoparticle composite. The nanoparticle composite of the present invention exhibits a stable and continuous drug release pattern irrespective of the solubility of the drug and has excellent tumor targeting due to its good in vivo stability and improved redispersibility in aqueous solution.

    TEMPERATURE-SENSITIVE COMPOSITE AND METHOD FOR PREPARING SAME

    公开(公告)号:EP3434258A2

    公开(公告)日:2019-01-30

    申请号:EP17770526.6

    申请日:2017-03-14

    发明人: YUK, Soon Hong

    摘要: The present invention relates to a temperature-sensitive composite and a method for preparing the same. The temperature-sensitive composite according to the present invention is maintained in a liquid state at room temperature and solidified at the time of delivery in the body, and shows remarkably excellent improvement in mechanical properties compared with an existing temperature-sensitive polymer composite, and as a result, the temperature-sensitive composite can promote the stability of a drug delivery system in the body and the sustainment of drug release.