公开(公告)号：EP2833150A1

公开(公告)日：2015-02-04

申请号：EP13770375.7

申请日：2013-03-28

申请人： Kyoto University

发明人： NAKAYAMA, Kenji ,  SHIMIZU, Kazuharu ,  UTSUMI, Jun ,  INOUE, Takahiro ,  OGAWA, Osamu

IPC分类号： G01N33/68 ,  G01N27/62

CPC分类号： G01N33/493 ,  C12N9/6424 ,  C12Y304/21077 ,  G01N33/57434 ,  G01N33/6851

摘要： A novel method that enables prostate cancer testing that is noninvasive and more accurate than conventional methods is disclosed. The present inventors intensively analyzed urine samples from prostate cancer patients, and non-cancer subjects, who are free of prostate cancer, and, as a result, newly discovered urinary peptides that can be used as indicators in prostate cancer testing. Use of these urinary peptides as indicators enables various prostate cancer-related tests including detection of prostate cancer, discrimination between prostate cancer and benign prostatic hyperplasia, monitoring of a therapeutic effect of prostate cancer therapy and monitoring of postoperative recurrence.

摘要翻译： 公开了一种能够进行前列腺癌检测的新方法，其非侵入性并且比常规方法更准确。 本发明人深入分析了前列腺癌患者和无癌前病人的非癌症患者的尿液样品，结果是新发现的可用作前列腺癌检测指标的尿肽。 使用这些尿肽作为指标，可以进行各种前列腺癌相关测试，包括前列腺癌的检测，前列腺癌和良性前列腺增生之间的区别，监测前列腺癌治疗的治疗效果和监测术后复发。