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1.发明授权HUMANIZED ANTIBODY AGAINST FIBROBLAST GROWTH FACTOR-8 AND FRAGMENT OF THE ANTIBODY 有权人源化抗体靶向成纤维细胞生长因子8和抗体片段
公开(公告)号：EP1422243B1
公开(公告)日：2008-04-23
申请号：EP02743765.6
申请日：2002-06-28
发明人： SHITARA, Kenya, c/o Kyowa Hakko Kogyo Co., Ltd. , NAKAMURA, Kazuyasu c/o Kyowa Hakko Kogyo Co., Ltd. , HIROTA, Maiko, c/o Kyowa Hakko Kogyo Co., Ltd. , SHIMADA, Naoki, c/o Kyowa Hakko Kogyo Co., Ltd.
IPC分类号： C07K16/18 , C12N15/13 , C12P21/08 , A61K39/395 , A61P35/00 , C12N1/15 , C12N1/19 , C12N1/21 , C12N5/00 , C07K16/22
CPC分类号： C07K16/22 , C07K2317/24 , C07K2317/50 , C07K2317/565 , C07K2317/73
摘要： An antibody, in particular, a humanized antibody against FGF-8; a fragment of the antibody; a DNA sequence encoding the antibody and the fragment thereof; a vector containing the DNA sequence; host cells transformed by the vector; a process for producing the above antibody and the fragment thereof using the above host cells; and remedies and diagnostics with the use of the antibody and the fragment thereof.
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2.发明公开HUMANIZED ANTIBODY AGAINST FIBROBLAST GROWTH FACTOR−8 AND FRAGMENT OF THE ANTIBODY 有权人造革防盗器GEGEN FIBROBLASTENWACHSTUMSFAKTOR 8 UND FRAGMENT DESANTIKÖRPERS
公开(公告)号：EP1422243A1
公开(公告)日：2004-05-26
申请号：EP02743765.6
申请日：2002-06-28
发明人： SHITARA, Kenya, c/o Kyowa Hakko Kogyo Co., Ltd. , NAKAMURA, K, c/o Kyowa Hakko Kogyo Co., Ltd. , HIROTA, Maiko, c/o Kyowa Hakko Kogyo Co., Ltd. , SHIMADA, Naoki, c/o Kyowa Hakko Kogyo Co., Ltd.
IPC分类号： C07K16/18 , C12N15/13 , C12P21/08 , A61K39/395 , A61P35/00 , C12N1/15 , C12N1/19 , C12N1/21 , C12N5/00
CPC分类号： C07K16/22 , C07K2317/24 , C07K2317/50 , C07K2317/565 , C07K2317/73
摘要： The present invention relates to an antibody against FGF-8, particularly a humanized antibody against FGF-8 and the antibody fragment thereof, a DNA sequence encoding the above antibody or the antibody fragment, a vector comprising the DNA sequence and a host cell transformed by the vector, a production process of the above antibody or the antibody fragment using the host cell, and a therapeutic agent and a diagnostic agent for cancer using the antibody or the antibody fragment.
摘要翻译： 本发明涉及针对FGF-8的抗体，特别是针对FGF-8的人源化抗体及其抗体片段，编码上述抗体或抗体片段的DNA序列，包含DNA序列的载体和由 载体，上述抗体的制备方法或使用该宿主细胞的抗体片段，以及使用该抗体或抗体片段的治疗剂和癌症诊断剂。
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