公开(公告)号：EP2125727A1

公开(公告)日：2009-12-02

申请号：EP07858162.6

申请日：2007-12-27

申请人： LACER, S.A.

发明人： REPOLLÉS MOLINER, José ,  PUBILL COY, Francisco ,  MOURELLE MANCINI, Marisabel ,  DEL CASTILLO NIETO, Juan Carlos ,  CABEZA LLORENTE, Lydia ,  MARTÍNEZ BONÍN, Juan ,  MODOLELL SALADRIGAS, Ana

IPC分类号： C07D211/54 ,  C07D401/06 ,  A61K31/44

CPC分类号： C07D335/02 ,  C07D211/54 ,  C07D211/70 ,  C07D401/12

摘要： The present invention relates to stable S-nitrosothiols derivatives of formula (I) having vasodilating effect and which inhibit the aggregation of the platelets and which therefore are useful for the preparation of medicaments for treatment of NO related diseases. The invention also relates to a process for the synthesis of the compounds of formula (I) and to intermediate compounds thereof.

公开(公告)号：EP2125727B1

公开(公告)日：2012-11-21

申请号：EP07858162.6

申请日：2007-12-27

申请人： LACER, S.A.

发明人： REPOLLÉS MOLINER, José ,  PUBILL COY, Francisco ,  MOURELLE MANCINI, Marisabel ,  DEL CASTILLO NIETO, Juan Carlos ,  CABEZA LLORENTE, Lydia ,  MARTÍNEZ BONÍN, Juan ,  MODOLELL SALADRIGAS, Ana

IPC分类号： C07D211/54 ,  C07D401/06 ,  A61K31/44

CPC分类号： C07D335/02 ,  C07D211/54 ,  C07D211/70 ,  C07D401/12