公开(公告)号：EP2408813A2

公开(公告)日：2012-01-25

申请号：EP10709546.5

申请日：2010-03-19

申请人： LFB Biotechnologies

发明人： BEHRENS, Christian ,  JORIEUX, Sylvie ,  KHARRAT, Abdelhakim ,  BOUAYADI, Khalil ,  MONDON, Philippe ,  MONNET-MARS, Céline

IPC分类号： C07K16/00

CPC分类号： C07K16/00 ,  C07K2317/21 ,  C07K2317/52 ,  C07K2317/92

摘要： The invention relates to a variant of a parent polypeptide comprising an Fc region, which variant exhibits increased binding to FcRn as compared to said parent polypeptide and comprises at least one amino acid modification in the Fc region.