公开(公告)号：EP4045536A1

公开(公告)日：2022-08-24

申请号：EP20875891.2

申请日：2020-10-16

Applicant: Lg Chem, Ltd.

Inventor： KIM, Yeonchul ,  LEE, Jaehyung ,  JUNG, Saem ,  LEE, Joon Hee ,  PARK, Gyeong Hyae ,  NA, Kyubong ,  MATTHEW, Vincent ,  AMRIK, Basran ,  EMMA, Stanley ,  EMMA, Jenkins ,  ESTELLE, Adam

IPC: C07K16/28 ,  C07K14/575 ,  A61K38/00 ,  A61P35/00 ,  A61K39/00

公开(公告)号：EP3978518A1

公开(公告)日：2022-04-06

申请号：EP20793990.1

申请日：2020-04-22

Applicant: LG CHEM, LTD.

Inventor： KIM, Yeonchul ,  MIN, Kyeongsik ,  SON, Young Dok ,  NA, Kyubong ,  HONG, Ji Ho ,  JUNG, Saem ,  JIN, Myung Won ,  PARK, Ji A ,  NOH, Soomin

IPC: C07K14/475 ,  A61K38/18 ,  A61K47/68 ,  A61P1/16 ,  A61P3/04 ,  A61P3/10

Abstract: Provided is a fusion polypeptide comprising GDF15 (Growth/differentiation factor 15) and an Fc region of immunoglobulin, a pharmaceutical composition comprising the fusion polypeptide, and a method of increasing in vivo duration of GDF15 comprising fusing with an Fc region of immunoglobulin.

公开(公告)号：EP4321178A1

公开(公告)日：2024-02-14

申请号：EP22784920.5

申请日：2022-04-05

Applicant: LG Chem, Ltd.

Inventor： NOH, Yoon Ae ,  LEE, Seungwon ,  KIM, Yeonchul ,  HUR, Ji Yeon ,  NA, Kyubong

IPC: A61K47/64 ,  A61K39/215 ,  A61K39/29 ,  A61K39/42 ,  A61K35/16 ,  A61P31/14 ,  A61P31/20 ,  A61K39/00

Abstract: The present invention relates to: a conjugate in which a receptor-binding domain (RBD) of coronavirus and a hepatitis B surface antigen (HBsAg) are linked; virus-like particles including the conjugate; and a coronavirus vaccine composition containing the conjugate and/or virus-like particles.

公开(公告)号：EP4071172A1

公开(公告)日：2022-10-12

申请号：EP20907118.2

申请日：2020-12-22

Applicant: Lg Chem, Ltd.

Inventor： CHOI, Yoon Aa ,  KIM, Jung A ,  JUNG, Saem ,  LEE, Ji Hyun ,  NA, Kyubong ,  KIM, Yeonchul ,  KIM, Han Byul

IPC: C07K16/28 ,  A61P35/00 ,  A61K39/00

Abstract: The present invention relates to an anti-LILRB1 antibody having increased specificity for LILRB1, and to uses thereof. Specifically, provided are an anti-LILRB1 antibody or antigen-binding fragment thereof, and uses thereof in treating cancer.

公开(公告)号：EP4071166A1

公开(公告)日：2022-10-12

申请号：EP20900221.1

申请日：2020-12-10

Applicant: Lg Chem, Ltd.

Inventor： KIM, Yeonchul ,  SON, Young Dok ,  NA, Kyubong ,  HONG, Ji Ho ,  JUNG, Saem ,  JIN, Myung Won ,  PARK, Ji A ,  NOH, Soomin ,  PARK, Hyuntaek

IPC: C07K14/475 ,  A61K38/18 ,  A61K47/68

Abstract: Disclosed are: a fusion polypeptide comprising growth differentiation factor 15 (GDF15) and a polypeptide region capable of O-glycosylation; a pharmaceutical composition comprising the fusion polypeptide; and a method for increasing the in vivo duration of GDF15, comprising the step of fusing a polypeptide region capable of O-glycosylation.

公开(公告)号：EP4063379A1

公开(公告)日：2022-09-28

申请号：EP20895099.8

申请日：2020-12-01

Applicant: LG Chem, Ltd.

Inventor： MIN, Byeong Eun ,  KIM, Yeonchul ,  PARK, Young Sam ,  JUNG, Saem

IPC: C07K7/08 ,  C07K14/52 ,  C07K14/47 ,  C12N9/02 ,  C12N9/18 ,  C12N9/90

Abstract: The present invention relates to a CHO cell-derived protein secretory factor, an expression cassette in which a nucleic acid sequence encoding the protein secretory factor; and a gene encoding a target protein are operably linked, an expression vector comprising the expression cassette, a transformed cell into which the expression vector is introduced, and a method for producing a target protein using the transformed cell.

公开(公告)号：EP3848388A1

公开(公告)日：2021-07-14

申请号：EP19857094.7

申请日：2019-09-04

Applicant: LG Chem, Ltd.

Inventor： KIM, Yeonchul ,  LEE, Seung Joo ,  KOH, Jong Uk ,  KIM, Kyuyong ,  JUNG, Saem ,  SON, Young Dok

IPC: C07K14/605 ,  C07K14/61 ,  C07K16/00 ,  A61K38/26 ,  A61K38/27 ,  A61K47/68

Abstract: Disclosed are: a fusion polypeptide comprising a target polypeptide and a hinge region of an immunoglobulin; a pharmaceutical composition containing the fusion polypeptide; and a method for increasing the in vivo period of a target polypeptide, comprising a step of fusing a hinge region of an immunoglobulin.