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公开(公告)号：EP1349572B1
公开(公告)日：2007-09-19
申请号：EP02729589.8
申请日：2002-01-09
发明人： KIM, Kyu-wan , JI, Hyi-jeong , LEE, Youn-kyeong , KIM, Wan-kyu , LEE, Hee-ku , KIM, Won-kyum
IPC分类号： A61K39/29
CPC分类号： A61K39/0017 , A61K39/0018 , A61K39/05 , A61K39/08 , A61K39/099 , A61K39/12 , A61K2039/521 , A61K2039/55505 , A61K2039/70 , C12N2730/10134
摘要： The present invention relates to a method for manufacturing a combined vaccine capable of concurrently preventing multiple diseases such as diphtheria, tetanus, pertussis, and hepatitis B which should be prevented in an infant. The method for manufacturing a combined vaccine according to the present invention includes the steps of independently adsorbing each protective antigen to an adsorbent of a aluminum hydroxide gel with respect to various diseases such as diphtheria, tetanus, pertussis, and hepatitis B which should be prevented in the infants, and combining each protective antigen adsorbed to the adsorbent after the adsorption. In the present invention, it is possible to concurrently prevent multiple diseases such as diphtheria, tetanus, pertussis, and hepatitis B which should be prevented in the infant using a combined vaccine manufactured according to the present invention.
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公开(公告)号：EP1349572A1
公开(公告)日：2003-10-08
申请号：EP02729589.8
申请日：2002-01-09
发明人： KIM, Kyu-wan , JI, Hyi-jeong , LEE, Youn-kyeong , KIM, Wan-kyu , LEE, Hee-ku , KIM, Won-kyum
IPC分类号： A61K39/29
CPC分类号： A61K39/0017 , A61K39/0018 , A61K39/05 , A61K39/08 , A61K39/099 , A61K39/12 , A61K2039/521 , A61K2039/55505 , A61K2039/70 , C12N2730/10134
摘要： The present invention relates to a method for manufacturing a combined vaccine capable of concurrently preventing multiple diseases such as diphtheria, tetanus, pertussis, and hepatitis B which should be prevented in an infant. The method for manufacturing a combined vaccine according to the present invention includes the steps of independently adsorbing each protective antigen to an adsorbent of a aluminum hydroxide gel with respect to various diseases such as diphtheria, tetanus, pertussis, and hepatitis B which should be prevented in the infants, and combining each protective antigen adsorbed to the adsorbent after the adsorption. In the present invention, it is possible to concurrently prevent multiple diseases such as diphtheria, tetanus, pertussis, and hepatitis B which should be prevented in the infant using a combined vaccine manufactured according to the present invention.
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