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公开(公告)号：EP2252272B1
公开(公告)日：2017-03-29
申请号：EP09721296.3
申请日：2009-02-27
发明人： ASMUSSEN, Bodo , SIMON, Michael
CPC分类号： A61K9/7007 , A61K9/006 , A61K9/2072
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公开(公告)号：EP2180885B1
公开(公告)日：2014-01-29
申请号：EP08841666.4
申请日：2008-08-21
发明人： ASMUSSEN, Bodo , SCHILLER, Christiane , WEITSCHIES, Werner , GARBACZ, Gregor , OMER-ADAM, Mahmoud A. , NAGEL, Stefan
IPC分类号： A61K9/52 , A61K9/20 , A61K36/064
CPC分类号： A61K9/0004 , A61K9/2072 , A61K9/2086 , A61K9/2866 , A61K36/064
摘要： Medicament for controlled release of medicinal substances in the medicament, comprises medically harmless, alcoholic fermentation enabled yeast. Independent claims are included for: (1) the preparation of the medicament for continuous release of medicinal substances, comprising pressing an active agent containing layer and yeast containing layer to form a double coated tablet, providing the double coated tablet with water permeable, gas proof coat and drilling an opening in the coat in the area of active agent containing layer; and (2) the preparation of the medicament for sudden release of medicinal substances, comprising adding the medicament and yeast into a sugar syrup, providing the obtained mixture with a water permeable, gas proof coat and then forming little balls.
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公开(公告)号：EP1208140B1
公开(公告)日：2006-06-28
申请号：EP00960450.5
申请日：2000-08-14
CPC分类号： B01J2/06 , A61J3/00 , A61K9/1652 , A61K9/4866
摘要： This invention relates to porous, rapidly decomposing, contain an active ingredient and pellets which are based on chitosan or an alkaline chitosan derivative manufactured by a dropping method in which an aqueous solution or dispersion of chitosan or an alkaline chitosan derivative, one or more active ingredients, optionally other additives and acid is added drop-wise into a cooling liquid with a maximum temperature of -5 DEG C and allowed to congeal drop by drop. The congealed droplets or pellets are then isolated and dried. The invention also relates to the use of said pellets in the manufacture of a medicament or a diagnostic product.
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公开(公告)号：EP1109541B8
公开(公告)日：2005-12-28
申请号：EP99944317.9
申请日：1999-07-31
发明人： ASMUSSEN, Bodo , HORSTMANN, Michael
CPC分类号： A61K9/009 , A61K9/0056 , A61K9/006 , A61K9/0065 , A61K9/2072 , A61K9/7007
摘要： The invention relates to a active ingredient support in the form of a film. Particles of a substrate containing an active ingredient are deposited on the surface of said support which is characterised in that said particles are solidly fixed onto the surface of said active ingredient in the form of a film or are embedded in said surface.
摘要翻译： 本发明涉及薄膜形式的活性成分载体。 含有活性成分的基质颗粒沉积在所述载体的表面上，其特征在于所述颗粒以膜的形式牢固地固定在所述活性成分的表面上或嵌入所述表面中。
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6.发明公开MAGENSAFTRESISTENTE VORRICHTUNG ZUR FREISETZUNG VON MUKOADHÄSIVEN WIRKSTOFFTRÄGERN UND VERFAHREN ZUR HERSTELLUNG DER MAGENSAFTRESISTENTEN VORRICHTUNG 有权FOR释放活性粘膜粘附承运人和方法GASTRO性器具，用于产生胃耐DEVICE
公开(公告)号：EP1383485A1
公开(公告)日：2004-01-28
申请号：EP02730183.7
申请日：2002-04-22
CPC分类号： A61K9/0065 , A61K9/0007 , A61K9/167 , A61K9/4891 , Y10T428/13
摘要： The invention relates to a gastric juice-resistant device, which is provided for releasing active substance excipients having a delayed intestinal passage from a gastric juice-resistant enclosure, and which serves to increase the concentration of active substances in the intestines. The inventive device is characterized in that the excipient containing at least one active substance is provided in the form of a multiparticulate preparation whose individual particles have mucoadhesive properties. The invention also relates to a method for producing said device.
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7.发明公开PHARMAZEUTISCHE ZUSAMMENSETZUNG ENTHALTEND DESOXYPEGANIN ZUR BEHANDLUNG DER NIKOTINABHÄNGIGKEIT 有权用药物组合物含desoxypeganine烟碱依赖治疗肩周炎
公开(公告)号：EP1150681A2
公开(公告)日：2001-11-07
申请号：EP00905035.2
申请日：2000-02-08
IPC分类号： A61K31/519 , A61P25/34
CPC分类号： A61K31/517 , Y10S514/813
摘要： Desoxypeganine and its pharmaceutically acceptable acid addition salts can be used in the treatment of nicotine dependence. Said substances are administered preferably in a continuos and controlled manner. The pharmaceutical administration form enables controlled release, e.g. for oral, transdermal or another route of parenteral administration.
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8.发明公开TRANSDERMALES THERAPEUTISCHES SYSTEM MIT EINER SELBSTKLEBENDEN MATRIX, ENTHALTEND ORGANISCHE SÄURE-ADDITIONSSALZE VON ALKALOIDEN DES MORPHIN- BZW. MORPHINANTYPS 有权用粘合剂MATRIX含生物碱吗啡有机酸盐或透皮治疗系统 MORPHINANTYPS
公开(公告)号：EP1143938A2
公开(公告)日：2001-10-17
申请号：EP00901097.6
申请日：2000-01-13
发明人： KOCH, Andreas , ADAM, Bernd , MATUSCH, Rudolf , ASMUSSEN, Bodo
IPC分类号： A61K9/70 , A61K31/485
CPC分类号： A61K9/7061 , A61K31/485
摘要： The invention relates to a transdermal therapeutic system (TTS) comprising a support layer which is impermeable to the active ingredient, a self-adhesive matrix consisting of a cationic base polymer and a detachable protective film on the side facing the skin. As active ingredient the matrix contains organic acid addition salts of morphine alkaloids on the basis of a water-soluble polyaminomethacrylate salt containing fatty acids. The invention is characterized in that a sparingly water-soluble copolymer of acrylic and methacrylic acid esters with a comparatively low quaternary content of ammonium groups which form a salt with inorganic acids is admixed to the cationic base polymer.
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公开(公告)号：EP1799579B1
公开(公告)日：2012-10-31
申请号：EP05787419.0
申请日：2005-09-10
发明人： SIMON, Michael , KRUMME, Markus , LUDWIG, Karin , ASMUSSEN, Bodo
CPC分类号： B65D50/06 , B65D75/5805 , B65D2215/04 , B65D2575/362
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公开(公告)号：EP2094105B1
公开(公告)日：2011-10-26
申请号：EP07856636.1
申请日：2007-12-12
CPC分类号： A23L27/74 , A23L27/79 , A23V2002/00 , A61K9/0056 , C08L3/08 , A23V2250/50 , A23V2200/222 , A23V2250/24 , A23V2250/02 , A23V2200/15 , A23V2250/5118
摘要： The invention relates to edible foil-shaped coke-flavored preparations which quickly disintegrate in a residue-free manner when coming in contact with moisture.
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