公开(公告)号：EP3331506A1

公开(公告)日：2018-06-13

申请号：EP16770468.3

申请日：2016-09-16

申请人： Laboratoires C.T.R.S.

发明人： DESCHAMPS, Bernard ,  FERRY, Antoine ,  VOGEL, Andreas

IPC分类号： A61K9/26 ,  A61K9/50 ,  A61K31/575

CPC分类号： A61K9/5026 ,  A61K9/2081 ,  A61K9/4866 ,  A61K9/5089 ,  A61K31/575 ,  A61P1/16

摘要： The present invention relates to pediatric drug formulation. Especially, this invention relates to the manufacturing of granules comprising a core comprising a drug having an unpleasant taste, which may be a primary bile acid, such as for example cholic acid, and a taste-masking coating. The purpose of the invention is to fully mask unpleasant taste of the drug, while ensuring its availability at the duodenum biological site.

公开(公告)号：EP3331506B1

公开(公告)日：2019-03-20

申请号：EP16770468.3

申请日：2016-09-16

申请人： Laboratoires C.T.R.S.

发明人： DESCHAMPS, Bernard ,  FERRY, Antoine ,  VOGEL, Andreas

IPC分类号： A61K9/26 ,  A61K9/50 ,  A61K9/48 ,  A61K31/575 ,  A61P1/16