公开(公告)号：EP4201938A1

公开(公告)日：2023-06-28

申请号：EP22755561.2

申请日：2022-02-17

申请人： Lanzhou University ,  Tencent Technology (Shenzhen) Company Limited

发明人： BAI, Qifeng ,  XU, Tingyang ,  FENG, Liya ,  LIU, Shuo ,  HUANG, Junzhou ,  LIU, Huanxiang ,  YAO, Xiaojun

IPC分类号： C07D495/04 ,  A61K31/4365 ,  A61P3/10

摘要： The present disclosure relates to the field of medical technologies, and provides a compound and use thereof as a glucagon receptor antagonist. The compound includes a compound A, or an isomer, metabolite, prodrug, pharmaceutically acceptable ester, or pharmaceutically acceptable salt of the compound A. The glucagon receptor antagonist in the present disclosure has a novel skeleton structure and a low half maximal inhibitory concentration on the glucagon receptor.