公开(公告)号：EP3356357A1

公开(公告)日：2018-08-08

申请号：EP16850453.8

申请日：2016-09-30

申请人： LegoChem Biosciences, Inc.

发明人： CHANG, Hye, Kyung ,  BAEK, Sung, Yoon ,  KIM, Min, Jung ,  OH, Kyu, Man ,  CHOI, Jeung, Soon ,  HA, Soo, Bong ,  KIM, Sung, Min ,  CHUNG, Chul-Woong ,  KANG, Dae, Hyuck ,  KWON, Hyun, Jin ,  CHO, Young, Lag ,  KIM, Yong, Zu

IPC分类号： C07D413/04 ,  C07D471/08 ,  C07D487/08 ,  A61K31/437 ,  A61K31/42

CPC分类号： C07D471/08 ,  A61K31/46 ,  C07D519/00

摘要： Substituted dihydroisoxazole derivatives useful as inhibitors of β-lactamases are provided. The invention further provides medical uses of substituted dihydroisoxazole derivatives, for example, as antibacterial agents.