专利检索 ap:("Lek, Tovarna Farmacevtskih In Kemicnih Izdelkov D.D.") AND inv:"REBIC, Ljubomira, Barbara;" 第 1 页

1.

发明公开
DIRECTLY COMPRESSIBLE MATRIX FOR CONTROLLED RELEASE OF SINGLE DAILY DOSES OF CLARITHROMYCIN 有权
标题翻译： DIREKTVERPRESSBARE矩阵的克拉霉素，每日一次剂量的控制分布

公开(公告)号：EP1150686A1

公开(公告)日：2001-11-07

申请号：EP00905514.6

申请日：2000-02-17

申请人： Lek, Tovarna Farmacevtskih In Kemicnih Izdelkov D.D.

发明人： FERCEJ TEMELJOTOV, Darja; , MOHAR, Milojka; , SALOBIR, Mateja , REBIC, Ljubomira, Barbara; , OPRESNIK, Marko

IPC分类号： A61K31/70 , A61K9/20 , A61K9/28

CPC分类号： A61K31/7048 , A61K9/2013 , A61K9/2054 , A61K9/2866

摘要： The invention refers to an improved pharmaceutical formulation for controlled release of clarithromycin or its derivatives, enabled by a novel combined matrix consisting of a fatty and a hydrophilic component, whereto also a surfactant and a pH-modulator may be added when an additional influence on the release profile of the active substance is desired.