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1.发明公开Non-surgical removal of localized fat accumulation with a bile salt in conjunction with an analgesic or anti-inflammatory agent 审中-公开使用胆汁盐的，与用于非手术去除油脂的止痛剂或抗炎剂一起
公开(公告)号：EP2550968A1
公开(公告)日：2013-01-30
申请号：EP12189943.9
申请日：2005-02-08
申请人： Los Angeles Biomedical Research Institute at Harbor-UCLA Medical Center , The Regents of the University of California
IPC分类号： A61K31/575 , A61P3/00 , A61Q19/06 , A61K31/222 , A61K31/60 , A61K45/06 , A61K9/00
CPC分类号： A61K31/575 , A61K8/63 , A61K9/0019 , A61K31/685 , A61K45/06 , A61K2800/30 , A61K2800/91 , A61Q19/06 , A61K2300/00
摘要： Compositions and methods useful in the non-surgical removal of localized fat deposits in patients in need thereof using pharmacologically active detergents are disclosed. The pharmacologically active detergent compositions can additionally include anti-inflammatory agents, analgesics, dispersion agents and pharmaceutically acceptable excipients but do not contain phosphotidylcholine. The pharmacologically active detergents compositions are useful for treating localized accumulations of fat including lower eyelid fat herniation, lipodystrophy and fat deposits associated with cellulite and do not require surgical procedures such as liposuction.
摘要翻译： 组合物和方法及其使用的药理学活性洗涤剂在有需要的病人的非外科手术去除局部脂肪沉积物的有用的游离缺失盘。 药理活性的洗涤剂组合物可另外包括抗炎剂，止痛剂，分散剂和药学上可接受的赋形剂，但不包含磷脂酰胆碱。 药理活性的洗涤剂组合物用于治疗包括下眼睑脂肪疝，脂肪代谢障碍和脂肪堆积橘皮相关的，并且不需要外科手术的局部脂肪堆积有用：如吸脂术。
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2.发明公开Injectable coposition comprising sodium deoxycholate 有权Injizierbare Zusammensetzung enthaltend Natrium脱氧胆酸盐
公开(公告)号：EP2422789A1
公开(公告)日：2012-02-29
申请号：EP11166225.0
申请日：2005-02-08
申请人： Los Angeles Biomedical Research Institute at Harbor-UCLA Medical Center , The Regents of the University of California
IPC分类号： A61K31/575 , A61K31/765 , A61K31/205 , A61P3/00 , A61Q19/06
CPC分类号： A61K31/575 , A61K8/63 , A61K9/0019 , A61K31/685 , A61K45/06 , A61K2800/30 , A61K2800/91 , A61Q19/06 , A61K2300/00
摘要： Compositions and methods useful in the non-surgical removal of localized fat deposits in patients in need thereof using pharmacologically active detergents are disclosed. The pharmacologically active detergent compositions can additionally include anti-inflammatory agents, analgesics, dispersion agents and pharmaceutically acceptable excipients but do not contain phosphotidylcholine. The pharmacologically active detergents compositions are useful for treating localized accumulations of fat including lower eyelid fat herniation, lipodystrophy and fat deposits associated with cellulite and do not require surgical procedures such as liposuction.
摘要翻译： 公开了可用于使用药理活性洗涤剂非需要的患者非手术去除局部脂肪沉积物的组合物和方法。 药理活性的洗涤剂组合物可另外包含抗炎剂，止痛剂，分散剂和药学上可接受的赋形剂，但不含磷脂酰胆碱。 药理活性洗涤剂组合物可用于治疗脂肪的局部积聚，包括下眼睑脂肪突出症，脂肪营养不良和与脂肪团相关的脂肪沉积物，并且不需要外科手术如抽脂。
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公开(公告)号：EP2380576B1
公开(公告)日：2020-04-08
申请号：EP11166230.0
申请日：2005-05-19
申请人： Los Angeles Biomedical Research Institute at Harbor-UCLA Medical Center , The Regents of the University of California
IPC分类号： A61Q19/06 , A61K31/575 , A61P3/04
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公开(公告)号：EP2422789B1
公开(公告)日：2017-11-22
申请号：EP11166225.0
申请日：2005-02-08
申请人： Los Angeles Biomedical Research Institute at Harbor-UCLA Medical Center , The Regents of the University of California
IPC分类号： A61K31/575 , A61K31/765 , A61K31/205 , A61P3/00 , A61Q19/06
CPC分类号： A61K31/575 , A61K8/63 , A61K9/0019 , A61K31/685 , A61K45/06 , A61K2800/30 , A61K2800/91 , A61Q19/06 , A61K2300/00
摘要： Compositions and methods useful in the non-surgical removal of localized fat deposits in patients in need thereof using pharmacologically active detergents are disclosed. The pharmacologically active detergent compositions can additionally include anti-inflammatory agents, analgesics, dispersion agents and pharmaceutically acceptable excipients but do not contain phosphotidylcholine. The pharmacologically active detergents compositions are useful for treating localized accumulations of fat including lower eyelid fat herniation, lipodystrophy and fat deposits associated with cellulite and do not require surgical procedures such as liposuction.
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5.发明公开Methods and related compositions for reduction of fat 审中-公开法国和德国人Zusammensetzungen zur Fettreduzierung
公开(公告)号：EP2380576A2
公开(公告)日：2011-10-26
申请号：EP11166230.0
申请日：2005-05-19
申请人： Los Angeles Biomedical Research Institute at Harbor-UCLA Medical Center , The Regents of the University of California
IPC分类号： A61K31/575 , A61K31/765 , A61K31/205 , A61P3/00
摘要： Compositions and methods useful in the reduction of localized fat deposits in patients in need thereof using pharmacologically active detergents are disclosed. The pharmacologically active detergent compositions can additionally include anti-inflammatory agents, analgesics, dispersion or anti-dispersion agents and pharmaceutically acceptable excipients. The pharmacologically active detergents compositions are useful for treating localized accumulations of fat including, for example, lower eyelid fat herniation, lipodystrophy grid fat deposits associated with cellulite and do not require surgical procedures such as liposuction.
摘要翻译： 公开了可用于使用药理活性洗涤剂在有需要的患者中减少局部脂肪沉积的组合物和方法。 药理活性的洗涤剂组合物可另外包括抗炎剂，止痛剂，分散体或抗分散剂和药学上可接受的赋形剂。 药理活性洗涤剂组合物可用于治疗脂肪的局部积聚，包括例如下眼睑脂肪突出症，与脂肪团相关的脂肪营养不良网格脂肪沉积物，并且不需要外科手术如抽脂。
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公开(公告)号：EP2572718A1
公开(公告)日：2013-03-27
申请号：EP12189947.0
申请日：2005-05-19
申请人： Los Angeles Biomedical Research Institute at Harbor-UCLA Medical Center , The Regents of the University of California
IPC分类号： A61K31/575 , A61P3/00 , A61Q19/06 , A61K8/63 , A61K31/685
CPC分类号： A61K31/575 , A61K8/63 , A61K9/0019 , A61K31/685 , A61K45/06 , A61K2800/30 , A61K2800/91 , A61Q19/06 , A61K2300/00
摘要： Compositions and methods useful in the reduction of localized fat deposits in patients in need thereof using pharmacologically active detergents are disclosed. The pharmacologically active detergent compositions can additionally include anti-inflammatory agents, analgesics, dispersion or anti-dispersion agents and pharmaceutically acceptable excipients. The pharmacologically active detergents compositions are useful for treating localized accumulations of fat including, for example, lower eyelid fat herniation, lipodystrophy grid fat deposits associated with cellulite and do not require surgical procedures such as liposuction.
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7.发明公开Methods and related compositions for reduction of fat 审中-公开法国和德国人Zusammensetzungen zur Fettreduzierung
公开(公告)号：EP2380576A3
公开(公告)日：2012-02-22
申请号：EP11166230.0
申请日：2005-05-19
申请人： Los Angeles Biomedical Research Institute at Harbor-UCLA Medical Center , The Regents of the University of California
IPC分类号： A61K31/575 , A61K31/765 , A61K31/205 , A61P3/00 , A61Q19/06
摘要： Compositions and methods useful in the reduction of localized fat deposits in patients in need thereof using pharmacologically active detergents are disclosed. The pharmacologically active detergent compositions can additionally include anti-inflammatory agents, analgesics, dispersion or anti-dispersion agents and pharmaceutically acceptable excipients. The pharmacologically active detergents compositions are useful for treating localized accumulations of fat including, for example, lower eyelid fat herniation, lipodystrophy grid fat deposits associated with cellulite and do not require surgical procedures such as liposuction.
摘要翻译： 公开了可用于使用药理活性洗涤剂非需要的患者非手术去除局部脂肪沉积物的组合物和方法。 药理活性的洗涤剂组合物可另外包含抗炎剂，止痛剂，分散剂和药学上可接受的赋形剂，但不含磷脂酰胆碱。 药理活性洗涤剂组合物可用于治疗脂肪的局部积聚，包括下眼睑脂肪突出症，脂肪营养不良和与脂肪团相关的脂肪沉积物，并且不需要外科手术如抽脂。
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