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公开(公告)号:EP2820041A1
公开(公告)日:2015-01-07
申请号:EP13710227.3
申请日:2013-03-01
申请人: Ludwig Institute For Cancer Research Ltd. , Chancellors, Masters & Scholars of the University of Oxford
IPC分类号: C07K16/00 , C07K14/00 , G01N33/574 , G06F19/00 , A61P35/00
CPC分类号: G01N33/57496 , A61K2039/505 , C07K14/4703 , C07K14/4746 , C07K16/18 , C07K16/30 , C07K16/44 , C07K2317/34 , C07K2317/76 , G01N2333/4704 , G01N2333/4748 , G01N2440/14 , G01N2800/56 , G06F19/00 , G16H50/30
摘要: Described herein are methods of evaluating metastatic potential of a cancer based on the phosphorylation state and/or intracellular localization of iASPP. Therapeutic regimens designed based on the results of the diagnostic methods are also provided.
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公开(公告)号:EP2820041B1
公开(公告)日:2017-06-14
申请号:EP13710227.3
申请日:2013-03-01
申请人: Ludwig Institute For Cancer Research Ltd. , Chancellors, Masters & Scholars of the University of Oxford
IPC分类号: C07K16/00 , C07K14/00 , G01N33/574 , G06F19/00 , A61P35/00
CPC分类号: G01N33/57496 , A61K2039/505 , C07K14/4703 , C07K14/4746 , C07K16/18 , C07K16/30 , C07K16/44 , C07K2317/34 , C07K2317/76 , G01N2333/4704 , G01N2333/4748 , G01N2440/14 , G01N2800/56 , G06F19/00 , G16H50/30
摘要: Described herein are methods of evaluating metastatic potential of a cancer based on the phosphorylation state and/or intracellular localization of iASPP. Therapeutic regimens designed based on the results of the diagnostic methods are also provided.
摘要翻译: 本文描述了基于iASPP的磷酸化状态和/或细胞内定位评估癌症的转移潜能的方法。 还提供了基于诊断方法结果设计的治疗方案。
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