专利检索 ap:("Ludwig-Maximilians-Universität München" OR "Technische Universität München") AND inv:"ELFINGER, Markus" 第 1 页

1.

发明公开
TRANSPORT OF NANO- AND MACROMOLECULAR STRUCTURES INTO CYTOPLASM AND NUCLEUS OF CELLS 审中-公开
标题翻译：运输及性纳米结构的分子INS细胞质的宏观和在细胞核

公开(公告)号：EP1850876A1

公开(公告)日：2007-11-07

申请号：EP06706965.8

申请日：2006-02-15

申请人： Ludwig-Maximilians-Universität München , Technische Universität München

发明人： ROSENECKER, Joseph , RUDOLPH, Carsten , PLANK, Christian , ELFINGER, Markus

IPC分类号： A61K47/48

CPC分类号： A61K47/6911 , A61K47/545

摘要： The present invention refers to novel conjugate molecules and their use or the transport of nano- and macromolecular structures into cells and/or the nucleus. More particularly, the present invention refers to conjugate molecules containing a carrier, preferably thiopyridyl moieties, and a cargo moiety. Thereby, the thiopyridyl moiety is bound to the cargo moiety to act as a carrier, particularly for efficient intracellular and/or intranuclear delivery of drugs, nano-or macromolecular structures, etc.. The novel conjugate molecules are provided for the manufacture of a medicament for gene therapy, apoptosis, or for the treatment of diseases such as cancer, autoimmune diseases or infectious diseases.