专利检索 ap:("Luoxin Pharmaceutical (Shanghai) Co., Ltd." OR "Shandong Luoxin Pharmaceutical Group Stock Co., Ltd.") AND inv:"HE, Huijun" 第 1 页

1.

发明授权
INDOLO-SUBSTITUTED-PIPERIDINE COMPOUNDS AS ESTROGEN RECEPTOR DEGRADING AGENT 有权

公开(公告)号：EP3434668B1

公开(公告)日：2020-08-26

申请号：EP17769483.3

申请日：2017-03-24

申请人： Luoxin Pharmaceutical (Shanghai) Co., Ltd. , Shandong Luoxin Pharmaceutical Group Stock Co., Ltd.

发明人： LU, Jianyu , DING, Charles Z. , HU, Lihong , HE, Huijun , CHEN, Shuhui , DONG, Jiaqiang , WANG, Tie-Lin

IPC分类号： C07D209/18 , C07D409/06 , C07D403/12 , A61K31/404 , A61P35/00

2.

发明公开
SALT FORM OF ESTROGEN RECEPTOR DOWNREGULATOR, CRYSTALLINE FORM THEREOF, AND PREPARATION METHOD THEREFOR 审中-公开

公开(公告)号：EP3889136A1

公开(公告)日：2021-10-06

申请号：EP19888746.5

申请日：2019-10-17

申请人： Luoxin Pharmaceutical (Shanghai) Co., Ltd. , Shandong Luoxin Pharmaceutical Group Stock Co., Ltd.

发明人： HE, Huijun , SHI, Shenyi , LU, Jianyu , DING, Charles Z. , HU, Lihong , SHI, Bin , YANG, Wenqian , DONG, Jiaqiang , WANG, Tie-Lin

IPC分类号： C07D209/18 , A61K31/404 , A61P35/00

摘要： Provided are a salt form of an estrogen receptor down-regulator, a crystalline form thereof, and a preparation method therefor.

3.

发明公开
INDOLO-SUBSTITUTED-PIPERIDINE COMPOUNDS AS ESTROGEN RECEPTOR DEGRADING AGENT 审中-公开

公开(公告)号：EP3434668A1

公开(公告)日：2019-01-30

申请号：EP17769483.3

申请日：2017-03-24

申请人： Luoxin Biotechnology (Shanghai) Co., Ltd. , Shandong Luoxin Pharmaceutical Group Stock Co., Ltd.

发明人： LU, Jianyu , DING, Charles Z. , HU, Lihong , HE, Huijun , CHEN, Shuhui , DONG, Jiaqiang , WANG, Tie-lin

IPC分类号： C07D209/18 , C07D409/06 , C07D403/12 , A61K31/404 , A61P35/00

摘要： Disclosed is a new indole compound, in particular, the compound as shown in formula (I), and a preparation method, pharmaceutical composition and use thereof as an estrogen receptor down-regulator in preparing drugs for treating estrogen receptor-positive breast cancer.