公开(公告)号：EP1978959B1

公开(公告)日：2011-11-09

申请号：EP06851953.7

申请日：2006-09-18

申请人： M's Science Corporation

发明人： SUN, Connie, L.

IPC分类号： A61K31/47 ,  C07D211/22 ,  C07D211/26 ,  C07D405/06 ,  C07D295/13 ,  C07D295/096 ,  C07D317/58

CPC分类号： A61K31/47 ,  C07D211/22 ,  C07D211/26 ,  C07D295/096 ,  C07D317/58 ,  C07D405/06

摘要： Compounds of general formula (I) in which R1, m, X, n, Y and R3 have any of the meanings given in the specification, have affinity for sigma receptors and are useful in the treatment of disorders of the central nervous system.

公开(公告)号：EP1976525B1

公开(公告)日：2010-11-03

申请号：EP07762989.7

申请日：2007-01-22

申请人： M's Science Corporation

发明人： LI, Xiaoyuan ,  SUN, Connie, L.

IPC分类号： A61K31/497 ,  A61K31/445 ,  A61P25/00

CPC分类号： C07D211/22 ,  C07D211/26 ,  C07D295/08 ,  C07D311/58 ,  C07D317/58 ,  C07D317/60 ,  C07D319/18 ,  C07D405/06

摘要： Compounds of general formula (Ia): in which R1, A1, m, X, n, Y and R3 have any of the meanings given in the specification, have affinity for sigma receptors and are useful in the treatment of disorders of the central nervous system.

公开(公告)号：EP1931347A2

公开(公告)日：2008-06-18

申请号：EP06800654.3

申请日：2006-08-02

申请人： M's Science Corporation

发明人： SUN, Connie, L.

IPC分类号： A61K31/496

CPC分类号： C07D295/096 ,  C07D295/03 ,  C07D295/033 ,  C07D295/073 ,  C07D317/58

摘要： Compounds of general formula (I) in which R1 and R0 have any of the meanings given in the specification have affinity for sigma receptors and are useful in the treatment of disorders of the central nervous system.

公开(公告)号：EP1978959A2

公开(公告)日：2008-10-15

申请号：EP06851953.7

申请日：2006-09-18

申请人： M's Science Corporation

发明人： SUN, Connie, L.

IPC分类号： A61K31/47

CPC分类号： A61K31/47 ,  C07D211/22 ,  C07D211/26 ,  C07D295/096 ,  C07D317/58 ,  C07D405/06

摘要： Compounds of general formula (I) in which R1, m, X, n, Y and R3 have any of the meanings given in the specification, have affinity for sigma receptors and are useful in the treatment of disorders of the central nervous system.

公开(公告)号：EP1976525A2

公开(公告)日：2008-10-08

申请号：EP07762989.7

申请日：2007-01-22

申请人： M's Science Corporation

发明人： LI, Xiaoyuan ,  SUN, Connie, L.

IPC分类号： A61K31/495

CPC分类号： C07D211/22 ,  C07D211/26 ,  C07D295/08 ,  C07D311/58 ,  C07D317/58 ,  C07D317/60 ,  C07D319/18 ,  C07D405/06

摘要： Compounds of general formula (Ia): in which R1, A1, m, X, n, Y and R3 have any of the meanings given in the specification, have affinity for sigma receptors and are useful in the treatment of disorders of the central nervous system.