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公开(公告)号:EP0773785A2
公开(公告)日:1997-05-21
申请号:EP95927034.0
申请日:1995-07-28
申请人: MEDICAL RESEARCH COUNCIL , THE WISTAR INSTITUTE OF ANATOMY AND BIOLOGY , THE UNIVERSITY COURT OF THE UNIVERSITY OF GLASGOW
发明人: MACLEAN, Alasdair, Roderick , BROWN, Susanne, Moira , FRASER, Nigel, William , RANDAZZO, Bruce, Paul
CPC分类号: C12N7/00 , A61K35/763 , C12N2710/16621 , C12N2710/16632
摘要: Use as an anti-cancer agent of a mutant herpes simplex virus wherein the mutant virus comprises a modification in the gamma 34.5 gene in the long repeat region (RL) such that the gamma 34.5 gene is non-functional, manufacture of medicaments and methods of testing cancer in mammals employing HSV mutant.
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公开(公告)号:EP0773785B1
公开(公告)日:2002-06-26
申请号:EP95927034.9
申请日:1995-07-28
申请人: THE UNIVERSITY COURT OF THE UNIVERSITY OF GLASGOW , THE WISTAR INSTITUTE OF ANATOMY AND BIOLOGY
发明人: MACLEAN, Alasdair, Roderick , BROWN, Susanne, Moira , FRASER, Nigel, William , RANDAZZO, Bruce, Paul
CPC分类号: C12N7/00 , A61K35/763 , C12N2710/16621 , C12N2710/16632
摘要: Use as an anti-cancer agent of a mutant herpes simplex virus wherein the mutant virus comprises a modification in the gamma 34.5 gene in the long repeat region (RL) such that the gamma 34.5 gene is non-functional, manufacture of medicaments and methods of testing cancer in mammals employing HSV mutant.
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