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    METHOD AND APPARATUS FOR MONITORING TISSUE FLUID CONTENT FOR USE IN AN IMPLANTABLE CARDIAC DEVICE
    1.
    发明公开
    METHOD AND APPARATUS FOR MONITORING TISSUE FLUID CONTENT FOR USE IN AN IMPLANTABLE CARDIAC DEVICE 有权
    用于监控组织的液体含量用在心脏设备IMPLANTIERABREN

    公开(公告)号：EP1682220A2

    公开(公告)日：2006-07-26

    申请号：EP04795265.0

    申请日：2004-10-14

    申请人： MEDTRONIC, INC.

    发明人： WANG, Li ,  CHO, Yong Kyun ,  KUEHN, Kevin ,  ZILLMER, Glenn, C.

    IPC分类号： A61N1/362 ,  A61B5/053

    CPC分类号： A61B5/4869 ,  A61B5/0537 ,  A61B5/0538 ,  A61B5/7203 ,  A61B5/7285 ,  A61N1/3627 ,  A61N1/36521 ,  A61N1/3962

    摘要： A fluid status monitoring system for use in implantable cardiac stimulation or monitoring devices is provided for monitoring changes in thoracic fluid content. A fluid status monitor includes excitation pulse generating and control circuitry, and voltage and current measurement and control circuitry for performing a series of cardiac-gated, intra-thoracic impedance measurements. The cardiac-gated measurements are filtered or time-averaged to provide a fluid status impedance value, with respiratory noise removed. Based on comparative analysis of the fluid status impedance value, a clinically relevant trend in fluid status may be tentatively diagnosed and a fluid status response provided. Cross-check intra-thoracic impedance measurements performed using the same or a different excitation pathway and a different measurement pathway than the primary intra-thoracic impedance measurement configuration may be used to verify a tentative diagnosis.

    METHOD AND APPARATUS FOR DISCRIMINATION OF ATRIAL FIBRILLATION USING VENTRICULAR RATE DETECTION
    2.
    发明公开
    METHOD AND APPARATUS FOR DISCRIMINATION OF ATRIAL FIBRILLATION USING VENTRICULAR RATE DETECTION 有权
    设备技术检测房颤心室检测

    公开(公告)号：EP1339453A2

    公开(公告)日：2003-09-03

    申请号：EP01994106.1

    申请日：2001-11-28

    申请人： Medtronic, Inc.

    发明人： BROWN, Mark, L. ,  WANG, Li

    IPC分类号： A61N1/37 ,  A61N1/362

    CPC分类号： A61B5/02405 ,  A61B5/0452 ,  A61B5/046 ,  A61B5/7232

    摘要： A method and apparatus for method for discriminating heart rhythms includes computing a first predetermined number of RR intervals from received QRS intervals, and computing a median RR interval corresponding to a predetermined number of the first predetermined number of RR intervals. A predetermined beat-to-beat variation and a corresponding predetermined count are determined based on the computed median RR interval. Beat-to-beat variation differences between the first predetermined number of RR intervals are computed and a determination is made as to whether the computed beat-to-beat variation differences are greater than the predetermined beat-to-beat variation, and as to whether a number of the computed beat-to-beat variation differences that are greater than the predetermined beat-to-beat variation is greater than the predetermined count. The heart rhythm is identified as an irregular rhythm in response to the number being greater than or equal to the predetermined count.

    METHOD AND APPARATUS FOR IMPEDANCE SIGNAL LOCALIZATIONS FROM IMPLANTED DEVICES
    4.
    发明公开
    METHOD AND APPARATUS FOR IMPEDANCE SIGNAL LOCALIZATIONS FROM IMPLANTED DEVICES 审中-公开
    装置植入设备的阻抗信号的本地化

    公开(公告)号：EP1628573A2

    公开(公告)日：2006-03-01

    申请号：EP04760256.0

    申请日：2004-04-14

    申请人： MEDTRONIC, INC.

    发明人： WANG, Li

    IPC分类号： A61B5/053 ,  A61N1/37 ,  A61N1/365

    CPC分类号： A61N1/36521 ,  A61B5/053 ,  A61B5/0809 ,  A61B5/7285

    摘要： Method and apparatus for monitoring a plurality of physiological factors contributing to physiological conditions of a heart, that determines a first impedance, corresponding to the plurality of physiological factors, across a plurality of vectors, and a second impedance, corresponding to the plurality of physiological factors, across the plurality of vectors subsequent to determining the first impedance. A relative change in impedance corresponding to the plurality of vectors is determined in response to the first impedance and the second impedance, first minimally contributing physiological factors of the plurality of physiological factors associated with a first physiological factor of the plurality of physiological factors are determined, and relative change in tissue resistivity corresponding to the first physiological factor in response to physiological factors of the plurality of physiological factors other than the first minimal contributing physiological factors and the relative change in impedance are determined.

    METHOD AND APPARATUS FOR DETECTING CHANGE IN INTRATHORACIC ELECTRICAL IMPEDANCE
    5.
    发明公开
    METHOD AND APPARATUS FOR DETECTING CHANGE IN INTRATHORACIC ELECTRICAL IMPEDANCE 有权
    GERÄTZUR DETEKTION VONÄNDERUNGENDER ELEKTRISCHEN THORAXIMPEDANZ

    公开(公告)号：EP1578488A1

    公开(公告)日：2005-09-28

    申请号：EP03796610.8

    申请日：2003-12-04

    申请人： MEDTRONIC, INC.

    发明人： STADLER, Robert, W. ,  WANG, Li

    IPC分类号： A61N1/365 ,  A61B5/00

    CPC分类号： A61B5/0538 ,  A61B5/0537 ,  A61B5/4875 ,  A61B5/686 ,  A61B5/7275 ,  A61N1/362 ,  A61N1/3627 ,  A61N1/36521 ,  G06F12/0862 ,  G06F12/0877

    摘要： A method and apparatus for detection of changes in impedance a patient that includes generating measured impedances, generating an adaptive baseline trend of the measured impedances corresponding to a first time period, generating a short term trend of the measured impedances corresponding to a second time period less than the first time period, and generating a metric of impedance change between the adaptive baseline trend and one of a most recent measured impedance and the short term trend of the measured impedances.

    摘要翻译： 一种用于检测患者阻抗变化的方法和装置，包括产生测量的阻抗，产生对应于第一时间段的所测量的阻抗的自适应基线趋势，产生对应于第二时间段的所测量的阻抗的短期趋势 确定短期趋势和基线趋势相对位置变化，确定相对位置变化对应于基线趋势与短期趋势的相交，确定基线趋势与计算周期之间的差异 平均阻力和累积，以确定基准趋势与短期趋势的相交，确定基线趋势与计算的周期平均阻抗之间的差异。

    METHODS AND APPARATUS FOR MANUALLY SUSPENDING INTRATHORACIC IMPEDANCE FLUID STATUS MEASUREMENTS
    6.
    发明公开
    METHODS AND APPARATUS FOR MANUALLY SUSPENDING INTRATHORACIC IMPEDANCE FLUID STATUS MEASUREMENTS 有权
    方法和装置手动插入胸腔内阻抗流体的状态测量

    公开(公告)号：EP2086398A1

    公开(公告)日：2009-08-12

    申请号：EP07863424.3

    申请日：2007-10-18

    申请人： MEDTRONIC, INC.

    发明人： VITENSE, Holly, S. ,  WANG, Li ,  DIRNBERGER, Denise ,  RHODES, Melissa, M. ,  HETTRICK, Douglas, A. ,  SARKAR, Shantanu

    IPC分类号： A61B5/00

    CPC分类号： A61N1/37258 ,  A61B5/0031 ,  A61B5/0215 ,  A61B5/053 ,  A61N1/37247 ,  G16H40/63

    摘要： The capability to suspend a patient alert relating to a monitored physiologic parameters addresses a need to selectively shut off a patient-alert signal or signals during the time a patient is being treated for an excursion in the parameter. Of course, in general a signal call attention to a patient's a potentially deleterious status or condition for which they should seek medical attention. Once a chronically-implanted monitoring device has detected or provided information about the parameter relative to a desired value, trend, or range and a clinician has been notified and intervened the alert signal is temporarily disabled for a predetermined period. That is, once the notification occurs and alert has served its purpose, the alert mechanism is selectively deactivated while the patient ostensibly begins to gradually correct the monitored physiologic parameter under a caregiver's direction and control. After which time, the alert will reactivate.

    APPARATUS FOR MONITORING TISSUE FLUID CONTENT FOR USE IN AN IMPLANTABLE CARDIAC DEVICE
    10.
    发明授权
    APPARATUS FOR MONITORING TISSUE FLUID CONTENT FOR USE IN AN IMPLANTABLE CARDIAC DEVICE 有权
    用于监控组织的液体含量用在心脏设备IMPLANTIERABREN

    公开(公告)号：EP1682220B1

    公开(公告)日：2010-05-19

    申请号：EP04795265.0

    申请日：2004-10-14

    申请人： Medtronic, Inc.

    发明人： WANG, Li ,  CHO, Yong Kyun ,  KUEHN, Kevin ,  ZILLMER, Glenn, C. ,  SHETH, Nirav, V

    IPC分类号： A61N1/362 ,  A61B5/053

    CPC分类号： A61B5/4869 ,  A61B5/0537 ,  A61B5/0538 ,  A61B5/7203 ,  A61B5/7285 ,  A61N1/3627 ,  A61N1/36521 ,  A61N1/3962

    摘要： A fluid status monitoring system for use in implantable cardiac stimulation or monitoring devices is provided for monitoring changes in thoracic fluid content. A fluid status monitor includes excitation pulse generating and control circuitry, and voltage and current measurement and control circuitry for performing a series of cardiac-gated, intra-thoracic impedance measurements. The cardiac-gated measurements are filtered or time-averaged to provide a fluid status impedance value, with respiratory noise removed. Based on comparative analysis of the fluid status impedance value, a clinically relevant trend in fluid status may be tentatively diagnosed and a fluid status response provided. Cross-check intra-thoracic impedance measurements performed using the same or a different excitation pathway and a different measurement pathway than the primary intra-thoracic impedance measurement configuration may be used to verify a tentative diagnosis.