公开(公告)号：EP1578487A4

公开(公告)日：2008-10-08

申请号：EP03809097

申请日：2003-10-15

申请人： MEDTRONIC INC

发明人： FREI MARK G ,  OSORIO IVAN ,  RISE MARK T ,  GIFTAKIS JONATHON E ,  GRAVES NINA M ,  CARLSON DAVID L ,  JENSEN RANDY M

IPC分类号： A61N1/08 ,  A61N1/32 ,  A61N1/36 ,  A61N2/00

CPC分类号： A61N1/37264 ,  A61N1/36146 ,  A61N2/00

摘要： Apparatuses and methods selectively blank a neurological channel of a medical device system (100) in the treatment of a nervous system disorder.

公开(公告)号：EP1583464A4

公开(公告)日：2008-12-17

申请号：EP03779123

申请日：2003-10-15

申请人： MEDTRONIC INC

发明人： FREI MARK G ,  OSORIO IVAN ,  GRAVES NINA M ,  SCHAFFNER SCOTT F ,  RISE MARK T ,  GIFTAKIS JONATHON E ,  CARLSON DAVID L

IPC分类号： A61B20060101 ,  A61B5/00 ,  A61B5/04 ,  A61B5/0476

CPC分类号： A61B5/04012 ,  A61B5/0476 ,  A61B5/4094 ,  A61B5/7217 ,  A61N1/36025 ,  A61N1/36082 ,  A61N1/361 ,  Y10S128/92

摘要： Apparatus and method detect a detection cluster that is associated with a neurological event, such as a seizure, of nervous system disorder and update therapy parameters that are associated with a treatment therapy. The occurrence of the detection cluster is detected when the maximal ratio exceeds an intensity threshold. If the maximal ratio drops below the intensity threshold for a time interval that is less than a time threshold and subsequently rises above the intensity threshold, the subsequent time duration is considered as being associated with the detection cluster rather than being associated with a different detection cluster. Consequently, treatment of the nervous system disorder during the corresponding time period is in accordance with one detection cluster. Treatment therapy may be provided by providing electrical stimulation, drug infusion or a combination. Therapy parameters may be updated for each mth successive group of applications of the treatment therapy or for each nth detection cluster.

公开(公告)号：EP1558131A4

公开(公告)日：2008-05-28

申请号：EP03809098

申请日：2003-10-15

申请人： MEDTRONIC INC

发明人： FREI MARK G ,  OSORIO IVAN ,  BHAVARAJU NARESH C ,  CARLSON DAVID L ,  GIFTAKIS JONATHON E ,  GRAVES NINA M

IPC分类号： A61N1/36 ,  A61B20060101 ,  A61B5/00 ,  A61B5/04 ,  A61B5/0476

CPC分类号： A61B5/04012 ,  A61B5/0476 ,  A61B5/4094 ,  A61B5/7217 ,  A61N1/36025 ,  A61N1/36082 ,  A61N1/361 ,  Y10S128/92

摘要： Apparatus (100) and method support a repetitive administration of a therapeutic treatment through a delivery unit (953) during a neurological event, such as a seizure, of a nervous system disorder. The medical device system monitors signal data from a sensor and through an amplifier. A neurological event is detected by a medical device system using a detection algorithm. Consequently, a electrical stimulation pulse is applied to an electrode. During the delivery of the electrical stimulation pulse, the medical device system blanks signal data that is associated with the electrode. Subsequently, additional blanking is providing during a time interval in which signal artifacts may occur and the amplifier is stabilizing. The medical device system then collects signal data for the detection algorithm to stabilize. Subsequently, the medical device system collects additional signal data in order to obtain statistically meaningful data. If the medical device system detects a continuation of the seizure, therapeutic treatment continues.

公开(公告)号：EP1558130A4

公开(公告)日：2009-01-28

申请号：EP03809096

申请日：2003-10-15

申请人： MEDTRONIC INC

发明人： OSORIO IVAN ,  FREI MARK G ,  BHAVARAJU NARESH C ,  PETERS THOMAS E ,  GRAVES NINA M ,  SCHAFFNER SCOTT F ,  GIFTAKIS JONATHON E ,  RISE MARK T ,  WERDER JONATHAN C

IPC分类号： A61B5/00 ,  A61B20060101 ,  A61B5/0476 ,  A61B17/52 ,  A61F7/00 ,  A61N1/00 ,  A61N2/00

CPC分类号： A61N1/08 ,  A61B5/0476 ,  A61B5/4094 ,  A61B5/7275 ,  A61N1/36025 ,  A61N1/36082 ,  A61N1/361 ,  A61N1/37217

摘要： Apparatus (100) and method support a neurological event screening for a medical device. The medical device (100) assists a user in determining a configuration of the medical device for delivering an effective treatment for a nervous system disorder. The medical device detects a neurological event, such as a seizure, and reports a neurological event focus location and a neurological event spread to the user. The user may use the information to provide a configuration of a therapeutic delivery unit and associated therapy parameters. Therapeutic treatment is delivered to the patient, and the medical device is provided an indication of the patient's acceptance to the treatment. The user may modify the configuration and therapy parameters in order to achieve efficacy and acceptance. Depending upon the patient's acceptance, therapy is applied in either an open loop mode or a closed loop mode. The medical device determines whether the treatment is successful in accordance with a criterion.

公开(公告)号：EP1558132A4

公开(公告)日：2007-02-14

申请号：EP03809112

申请日：2003-10-15

申请人： MEDTRONIC INC

发明人： OSORIO IVAN ,  FREI MARK G ,  GRAVES NINA M ,  GIFTAKIS JONATHON E

IPC分类号： A61B5/00 ,  A61B5/04 ,  A61B5/048 ,  A61N1/36 ,  A61N1/37 ,  A61N1/372 ,  G06F20060101

CPC分类号： A61N1/3702 ,  A61B5/048 ,  A61B5/4064 ,  A61B5/4094 ,  A61N1/36017 ,  A61N1/36064 ,  A61N1/36082 ,  A61N1/36135 ,  A61N1/37252 ,  Y10S128/92

摘要： A medical device system (100) capable of scoring a severity of sensed neurological signals relating to a nervous system disorder. The system comprises a monitoring element that receives a neurological signal having at least one event to be scored. The medical device system identifies one or more features of the neurological signal to use in scoring and computes a score of relative severity of the event using the identified feature. Once two or more events have been scored, the events may be ranked by severity relative to each other.