公开(公告)号：EP0794185A1

公开(公告)日：1997-09-10

申请号：EP95937193.1

申请日：1995-11-27

申请人： MEIJI SEIKA KABUSHIKI KAISHA

发明人： FUKUDA, Yoshimasa Pharmaceutical Research Center ,  HASEGAWA, Toshifumi Pharmaceutical Research Center ,  NAKATANI, Yuuko Pharmaceutical Research Center ,  MURASE, Kenshi Pharmaceutical Research Center ,  FUJI, Kazuyuki Pharmaceutical Research Center

IPC分类号： C07D519/00 ,  A61K31/425

CPC分类号： C07D513/04

摘要： A compound, represented by the following formula (I), having psychotropic effect is disclosed. A compound represented by the following formula (I) or a pharmaceutically acceptable salt thereof:
wherein

any one of R 1 and R 2 represents group W-(CH 2 ) m - wherein m is an integer of 1 to 4 with the other representing H or optionally substituted lower alkyl,
group W is a group represented by the following formula (i):
wherein
R 3 represents H or a halogen atom,
A represents O or S,
B represents N or CH, and
Y represents CH or N; and
ring structure -D- represents any one of the following formulae (a) to (d):
wherein
n is an integer of 0 to 2,
R 4 and R 5 each independently represent H, lower alkyl, a hydroxyl group, alkoxy, alkoxycarbonyl, or aminocarbonyl, and
a solid line accompanied by a dotted line represents a single bond or a double bond.