公开(公告)号：EP0759757B1

公开(公告)日：2002-08-21

申请号：EP95924570.5

申请日：1995-05-12

申请人： MERCK & CO., INC.

发明人： BRENNER, Gerald, S. ,  KATDARE, Ashok, V. ,  PRETZER, Denise ,  WHITEFORD, Donna, T.

IPC分类号： A61K31/66 ,  A61K9/00 ,  A61K47/12 ,  A61P19/08

CPC分类号： A61K9/0095 ,  A61K31/663

摘要： Disclosed is a therapy protocol for treating and for preventing bone loss in patients who have difficulty in swallowing by administering a liquid formulation of alendronate which can be easily swallowed. Also described are pharmaceutical dosage forms of a syrup, aqueous solution, a solution formed from a reconstituted powder, of alendronate, for carrying out the therapeutic method.

公开(公告)号：EP0759757A1

公开(公告)日：1997-03-05

申请号：EP95924570.0

申请日：1995-05-12

申请人： MERCK & CO., INC.

发明人： BRENNER, Gerald, S. ,  KATDARE, Ashok, V. ,  PRETZER, Denise ,  WHITEFORD, Donna, T.

IPC分类号： A61K9 ,  A61K31 ,  A61K47 ,  A61P19 ,  A61P29 ,  A61P35 ,  A61P43

CPC分类号： A61K9/0095 ,  A61K31/663

摘要： Disclosed is a therapy protocol for treating and for preventing bone loss in patients who have difficulty in swallowing by administering a liquid formulation of alendronate which can be easily swallowed. Also described are pharmaceutical dosage forms of a syrup, aqueous solution, a solution formed from a reconstituted powder, of alendronate, for carrying out the therapeutic method.