公开(公告)号：EP0466833B1

公开(公告)日：1997-09-10

申请号：EP90907508.7

申请日：1990-04-12

申请人： MERCK PATENT GmbH

发明人： ATKINSON, Anthony; ,  ELECTRICWALA, Asgar; ,  SAWYER, Roy, Thomas; ,  VON SICARD, Nils; ,  VOERMAN, Gerard

IPC分类号： C07K14/815 ,  A61K38/58

CPC分类号： C07K14/815 ,  A61K35/62 ,  A61K38/00 ,  Y10S514/902

摘要： This invention relates to a novel protease-inhibitor, - which we called GELIN - and to pharmaceutical and cosmetic preparations thereof, containing this compound. GELIN is an inhibitor of human and porcine leucocyte elastase and chymotrypsin. GELIN has specific antibiotic properties. It also relates to the novel use of EGLIN, another chymotrypsin-inhibitor in cosmetic preparations.