专利检索 ap:("MERCK SHARP & DOHME" OR "MSD R & D (CHINA) CO LTD") AND inv:"LOUGHRAN H MARIE" 第 1 页

1.

发明公开
PIPERAZINE DERIVATIVES AS HIV PROTEASE INHIBITORS 审中-公开
标题翻译： PIPERAZINDERIVATE ALS HIV-PROTEASEHEMMER

公开(公告)号：EP3116862A4

公开(公告)日：2017-08-30

申请号：EP15760695

申请日：2015-03-06

申请人： MERCK SHARP & DOHME , MSD R & D (CHINA) CO LTD

发明人： WILLIAMS PETER D , MCCAULEY JOHN A , BUNGARD CHRISTOPHER J , BENNETT DAVID JONATHAN , WADDELL SHERMAN T , MORRIELLO GREGORI J , CHANG LEHUA , DWYER MICHAEL P , HOLLOWAY M KATHARINE , CRESPO ALEJANDRO , CHU XIN-JIE , WISCOUNT CATHERINE , LOUGHRAN H MARIE , MANIKOWSKI JESSE J , KEERTIKAR KARTIK M , HU BIN , ZHONG BIN , JI TAO

IPC分类号： C07D513/08 , A61K31/554 , A61P31/18

CPC分类号： C07D513/08 , A61K31/554 , A61K45/06

摘要： The present invention is directed to compounds of Formula I pharmaceutical compositions comprising the same, and their use in the inhibition of HIV protease, the inhibition of HIV replication, the prophylaxis of infection by HIV, the treatment of infection by HIV, and the prophylaxis, treatment, and delay in the onset or progression of AIDS.

摘要翻译： 本发明涉及式I化合物，包含其的药物组合物，以及它们在抑制HIV蛋白酶，抑制HIV复制，预防HIV感染，治疗HIV感染以及预防，治疗和延缓艾滋病的发病或进展。

2.

发明公开
PIPERAZINE DERIVATIVES AS HIV PROTEASE INHIBITORS 审中-公开
标题翻译：哌嗪衍生物ALS HIV蛋白酶抑制剂

公开(公告)号：EP3027593A4

公开(公告)日：2017-03-29

申请号：EP14832049

申请日：2014-07-29

申请人： MERCK SHARP & DOHME , MSD R & D (CHINA) CO LTD

发明人： WILLIAMS PETER D , MCCAULEY JOHN A , BENNETT DAVID J , BUNGARD CHRISTOPHER J , CHANG LEHUA , CHU XIN-JIE , DWYER MICHAEL P , HOLLOWAY M KATHERINE , KEERTIKAR KARTIK M , LOUGHRAN H MARIE , MANIKOWSKI JESSE J , MORRIELLO GREGORI J , SHEN DONG-MING , SHERER EDWARD C , SCHULZ JURGEN , WADDELL SHERMAN TIM , WISCOUNT CATHERINE M , ZORN NICOLAS , SATYANARAYANA TUMMANAPALLI , VIJAYASARADHI SIVALENKA , HU BIN , JI TAO , ZHONG BIN

IPC分类号： C07D401/14 , A61K31/496 , A61P31/18 , C07D241/04 , C07D401/06 , C07D401/12 , C07D405/12 , C07D405/14 , C07D409/12 , C07D409/14 , C07D413/14 , C07D417/14

CPC分类号： C07D241/04 , C07D401/06 , C07D401/12 , C07D401/14 , C07D405/12 , C07D405/14 , C07D409/12 , C07D409/14 , C07D413/14 , C07D417/14

摘要： The present invention is directed to piperazine derivatives, pharmaceutical compositions comprising the same, and their use in the inhibition of HIV protease, the inhibition of HIV replication, the prophylaxis of infection by HIV, the treatment of infection by HIV, and the prophylaxis, treatment, and delay in the onset or progression of AIDS.