公开(公告)号：EP3221463A4

公开(公告)日：2018-07-25

申请号：EP15860608

申请日：2015-11-18

申请人： METABOLON INC

发明人： PERICHON REGIS ,  BELL LAUREN NICOLE ,  WULFF JACOB ,  NGUYEN UYEN THAO ,  WATKINS STEVEN M

IPC分类号： C12Q1/00 ,  G01N33/50 ,  G01N33/68

CPC分类号： G01N33/92 ,  G01N33/50 ,  G01N33/5023 ,  G01N33/6806 ,  G01N33/82 ,  G01N2560/00 ,  G01N2570/00 ,  G01N2800/085 ,  G01N2800/56 ,  G01N2800/7052

摘要： Biomarkers of NASH, NAFLD, and fibrosis and methods for diagnosis (or aiding in the diagnosis) of NAFLD, NASH and/or fibrosis are described herein. Additionally, methods of distinguishing between NAFLD and NASH, methods of classifying the stage of fibrosis, methods of determining the severity of liver disease, methods of determining the severity of liver disease or fibrosis, and methods of monitoring progression/regression of NASH, NAFLD, and/or fibrosis are described herein.