公开(公告)号：EP0460519A3

公开(公告)日：1992-04-08

申请号：EP91108764.1

申请日：1991-05-29

申请人： MILES INC.

发明人： Scott, William James

IPC分类号： G01N33/84 ,  G01N27/333

CPC分类号： G01N33/84 ,  Y10T436/108331 ,  Y10T436/193333

摘要： A heavy metal-free composition and its method of use in an ion selective electrode-based assay are disclosed. The heavy metal-free composition includes a borate compound and an alkalinity adjusting compound, and is used to dilute a test sample; buffer the test sample; and substantially reduce the affects of interferents present in the test sample on the ion selective electrode-based assay. The heavy metal-free composition and its method of use are especially useful in an ion selective electrode-based assay for carbonate ion concentration in a test sample, like blood serum, blood plasma, urine or cerebrospinal fluid.

公开(公告)号：EP0460519A2

公开(公告)日：1991-12-11

申请号：EP91108764.1

申请日：1991-05-29

申请人： MILES INC.

发明人： Scott, William James

IPC分类号： G01N33/84 ,  G01N27/333

CPC分类号： G01N33/84 ,  Y10T436/108331 ,  Y10T436/193333

摘要： A heavy metal-free composition and its method of use in an ion selective electrode-based assay are disclosed. The heavy metal-free composition includes a borate compound and an alkalinity adjusting compound, and is used to dilute a test sample; buffer the test sample; and substantially reduce the affects of interferents present in the test sample on the ion selective electrode-based assay. The heavy metal-free composition and its method of use are especially useful in an ion selective electrode-based assay for carbonate ion concentration in a test sample, like blood serum, blood plasma, urine or cerebrospinal fluid.

摘要翻译： 公开了一种不含重金属的组合物及其在基于离子选择电极的测定中的应用。 重金属组合物包括硼酸盐化合物和碱度调节化合物，并用于稀释测试样品; 缓冲试样; 并且基于离子选择电极的测定显着降低了测试样品中存在的干扰物的影响。 重金属组合物及其使用方法在用于测试样品中的碳酸根离子浓度的离子选择性电极基测定中是特别有用的，例如血清，血浆，尿液或脑脊髓液。