公开(公告)号：EP2379513A1

公开(公告)日：2011-10-26

申请号：EP09795675.9

申请日：2009-12-30

申请人： MILLENNIUM PHARMACEUTICALS, INC. ,  Sunesis Pharmaceuticals, Inc.

发明人： CHUAQUI, Claudio ,  COSSROW, Jennifer ,  DOWLING, James ,  GUAN, Bing ,  HOEMANN, Michael ,  ISHCHENKO, Alexey ,  JONES, John, Howard ,  KABIGTING, Lori ,  KUMARAVEL, Gnanasambandam ,  PENG, Hairuo ,  POWELL, Noel ,  RAIMUNDO, Brian ,  TANAKA, Hiroko ,  VAN VLOTEN, Kurt ,  VESSELS, Jeffrey ,  XIN, Zhili

IPC分类号： C07D261/08 ,  C07D409/12 ,  C07D413/14 ,  C07D417/12 ,  C07D417/14 ,  C07D471/04 ,  C07D487/04 ,  C07D413/12 ,  A61K31/416 ,  A61P35/00 ,  C07D513/04 ,  A61K31/437 ,  A61K31/422 ,  A61K31/428 ,  A61K31/429

CPC分类号： C07D261/08 ,  C07D409/12 ,  C07D413/12 ,  C07D413/14 ,  C07D417/12 ,  C07D417/14 ,  C07D471/04 ,  C07D487/04 ,  C07D513/04

摘要： The present invention provides compounds of formula (I) useful as inhibitors of Raf protein kinase. The present invention also provides compositions thereof, and methods of treating Raf -mediated diseases.