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1.发明公开
公开(公告)号：EP0553298A1
公开(公告)日：1993-08-04
申请号：EP92900942.0
申请日：1991-10-09
摘要： Formulations d'aérosol de solution pharmaceutique comprenant béclométhasone 17,21 dipropionate, éthanol ainsi qu'un propulseur choisi dans le groupe constitué de 1,1,1,2-tétrafluoroéthane, 1,1,1,2,3,3,3-heptafluoropropane, ainsi qu'un mélange de ceux-ci.
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公开(公告)号：EP0617610A1
公开(公告)日：1994-10-05
申请号：EP93901414.0
申请日：1992-12-11
发明人： SCHULTZ, Robert, K. , SCHULTZ, David, W. , OLIVER, Martin J. , MORIS, Robert, A. , JINKS, Philip A.
CPC分类号： A61K9/008 , A61K9/124 , A61K31/137 , A61K31/44
摘要： Formulations pharmaceutiques d'un aérosol en suspension, contenant une dose thérapeutique efficace d'un médicament, et du HFC 134a, du HFC 227, ou un mélange de ceux-ci.
摘要翻译： 含有有效治疗剂量的药物的悬浮液气雾剂和HFC 134a，HFC 227或其混合物的药物制剂。
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3.发明授权THE USE OF SOLUBLE FLUOROSURFACTANTS FOR THE PREPARATION OF METERED-DOSE AEROSOL FORMULATIONS 失效应用研究可溶性FLUOR含有表面活性剂用于生产气雾剂，随剂量供应。
公开(公告)号：EP0536204B1
公开(公告)日：1994-04-06
申请号：EP91911624.4
申请日：1991-06-21
摘要： Pharmaceutical suspension aerosol formulations using one or more perfluorinated sulfonamido alcohol phosphate esters as surface-active dispersing agents and 1,1,1,2-tetra-fluoroethane, 1,1,1,2,3,3,3-heptafluoropropane, or a mixture thereof, as the propellant.
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4.发明公开THE USE OF SOLUBLE FLUOROSURFACTANTS FOR THE PREPARATION OF METERED-DOSE AEROSOL FORMULATIONS 失效应用研究可溶性FLUOR含有表面活性剂用于生产气雾剂，随剂量供应。
公开(公告)号：EP0536204A1
公开(公告)日：1993-04-14
申请号：EP91911624.0
申请日：1991-06-21
摘要： Compositions pour aérosol contenant des suspensions pharmaceutiques utilisant un ou plusieurs esters de phosphate d'alcool sulfonamidoperfluorurés utilisés comme agents dispersants tensio-actifs et 1,1,1,2-tetra-fluoroéthane, 1,1,1,2,3,3,3-heptafluoropropane, ou un mélange de ceux-ci, comme gaz propulseur.
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公开(公告)号：EP1014944A2
公开(公告)日：2000-07-05
申请号：EP98904525.7
申请日：1998-02-04
发明人： STEFELY, James, S. , SCHULTZ, David, W. , SCHALLINGER, Luke, E. , PERMAN, Craig, A. , LEACH, Chester, L. , DUAN, Daniel, C.
CPC分类号： A61K9/0075 , A61K9/008 , A61K9/1647 , A61K47/593
摘要： Methods, compounds, and medicinal formulations utilizing biocompatible polymers for delivery of a drug, particularly for solubilizing, stabilizing and/or providing sustained release of drug from topical, implantable, and inhalation systems. Many of the methods, compounds, and medicinal formulations are particularly suitable for oral and/or nasal inhalation and use polymers of the formula -[X-R1-C(O)]- wherein each R1 is an independently selected organic group that links the -X- group to the carbonyl group, and each X is independently oxygen, sulfur, or catenary nitrogen.
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公开(公告)号：EP0617610B1
公开(公告)日：1997-03-19
申请号：EP93901414.8
申请日：1992-12-11
发明人： SCHULTZ, Robert, K. , SCHULTZ, David, W. , OLIVER, Martin J. , MORIS, Robert, A. , JINKS, Philip A.
CPC分类号： A61K9/008 , A61K9/124 , A61K31/137 , A61K31/44
摘要： Pharmaceutical suspension aerosol formulations containing a therapeutically effective amount of a drug and HFC 134a, HFC 227, or a mixture thereof.
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8.发明授权
公开(公告)号：EP1014944B1
公开(公告)日：2007-04-11
申请号：EP98904525.7
申请日：1998-02-04
发明人： STEFELY, James, S. , SCHULTZ, David, W. , SCHALLINGER, Luke, E. , PERMAN, Craig, A. , LEACH, Chester, L. , DUAN, Daniel, C.
CPC分类号： A61K9/0075 , A61K9/008 , A61K9/1647 , A61K47/593
摘要： Methods, compounds, and medicinal formulations utilizing biocompatible polymers for delivery of a drug, particularly for solubilizing, stabilizing and/or providing sustained release of drug from topical, implantable, and inhalation systems. Many of the methods, compounds, and medicinal formulations are particularly suitable for oral and/or nasal inhalation and use polymers of the formula -[X-R -C(O)]- wherein each R is an independently selected organic group that links the -X- group to the carbonyl group, and each X is independently oxygen, sulfur, or catenary nitrogen.
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9.发明授权AEROSOL FORMULATION CONTAINING AN ESTER-, AMIDE-, OR MERCAPTOESTER-DERIVED DISPERSING AID 失效气溶胶组合物含有OFF酯，酰胺或MERKAPTOESTER-衍生物分散剂
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10.发明公开AEROSOL FORMULATION CONTAINING AN ESTER-, AMIDE-, OR MERCAPTOESTER-DERIVED DISPERSING AID 失效气溶胶组合物含有OFF酯，酰胺或MERKAPTOESTER-衍生物分散剂
公开(公告)号：EP0689424A1
公开(公告)日：1996-01-03
申请号：EP94912238.0
申请日：1994-03-16
CPC分类号： A61K9/008
摘要： A medicinal aerosol formulation containing a particulate drug and a dispersing aid derived from a hydroxyacid, a mercapto acid, or an amino acid.
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