公开(公告)号：EP1928827B1

公开(公告)日：2012-08-22

申请号：EP06804229.0

申请日：2006-09-27

申请人： MYRIAD GENETICS, INC.

发明人： WEINER, Warren, S. ,  SLADE, Rachel, M. ,  KLIMOVA, Yevgeniya, I. ,  WALTON, Ruth, J. ,  ANDERSON, Mark, B.

IPC分类号： C07D209/00

CPC分类号： C07D207/327 ,  C07D207/325 ,  C07D207/33 ,  C07D207/34

摘要： Novel pyrrole derivatives are disclosed as Aβ42-lowering agents for the treatment and prevention of neurodegenerative disorders characterized by the formation or accumulation of amyloid plaques comprising the Aβ42 peptide.

公开(公告)号：EP1928827A2

公开(公告)日：2008-06-11

申请号：EP06804229.0

申请日：2006-09-27

申请人： MYRIAD GENETICS, INC.

发明人： WEINER, Warren, S. ,  SLADE, Rachel, M. ,  KLIMOVA, Yevgeniya, I. ,  WALTON, Ruth, J. ,  ANDERSON, Mark, B.

IPC分类号： C07D209/00

CPC分类号： C07D207/327 ,  C07D207/325 ,  C07D207/33 ,  C07D207/34

摘要： Novel pyrrole derivatives are disclosed as Aβ42-lowering agents for the treatment and prevention of neurodegenerative disorders characterized by the formation or accumulation of amyloid plaques comprising the Aβ42 peptide.