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    METHOD OF DETOXICATION OF YPERITE BY USING HALOALKANE DEHALOGENASES
    3.
    发明授权
    METHOD OF DETOXICATION OF YPERITE BY USING HALOALKANE DEHALOGENASES 有权
    利用卤代烷脱卤剂对白云石进行脱毒的方法

    公开(公告)号：EP1899022B8

    公开(公告)日：2013-12-18

    申请号：EP06753161.6

    申请日：2006-06-01

    申请人： Masarykova univerzita

    发明人： PROKOP, Zbynek ,  DAMBORSKY, Jiri ,  OPLUSTIL, Frantisek ,  JESENSKA, Andrea ,  NAGATA, Yuji

    IPC分类号： A62D3/02 ,  A62D101/02 ,  C02F3/34 ,  C02F11/00 ,  C02F11/02 ,  C02F101/36

    CPC分类号： A62D3/02 ,  A62D2101/02 ,  C02F3/34 ,  C02F11/004 ,  C02F11/02 ,  C02F2101/36 ,  C02F2209/06

    摘要： The method of detoxification of yperite—bis(2-chloroethyl)sulfide—by the use of a haloalkane dehalogenases or their compositions, the method of preparation of dehalogenationating enzymes and of decontamination compositions which contains at least one wild type and/or modified haloalkane dehalogenase (EC 3.8.1.5) as an chemically active component. The preferred dehalogenases are LinB from Sphingomonas paucimobilis UT26, DhaA from Rhodococcus rodochrous NCIMB 13064, DmbA from Mycobacterium bovis 5033/66. Decontamination is utilizable for detoxification of yperite from the surfaces of instrumentality, constructional objects, human or animal skin and elements of environment by the treatment of yperite with the detoxification composition according the invention at +10° C. to +70° C., preferably at about +40° C. and pH from 4 to 12.

    摘要翻译： 通过使用卤代烷脱卤素酶或它们的组合物，去除卤化物 - 双（2-氯乙基）硫化物的方法，制备脱卤化酶和去污组合物的方法，所述去污染组合物含有至少一种野生型和/或修饰的卤代烷脱卤素酶 （EC 3.8.1.5）作为化学活性成分。 优选的脱卤素酶是来自Sphingomonas paucimobilis UT26的LinB，来自棒状红球菌NCIMB 13064的DhaA，来自Mycobacterium bovis 5033/66的DmbA。 通过在+ 10℃至+ 70℃下用根据本发明的解毒组合物处理赤铁矿，净化可用于从工具，构造物体，人或动物皮肤和环境要素的表面解毒赤铁矿，优选 在约+ 40℃和4-12的pH下进行。

    METHOD OF DETOXICATION OF YPERITE BY USING HALOALKANE DEHALOGENASES
    4.
    发明公开
    METHOD OF DETOXICATION OF YPERITE BY USING HALOALKANE DEHALOGENASES 有权
    利用卤代烷脱卤剂对白云石进行脱毒的方法

    公开(公告)号：EP1899022A1

    公开(公告)日：2008-03-19

    申请号：EP06753161.6

    申请日：2006-06-01

    申请人： Masarykova univerzita

    发明人： PROKOP, Zbynek ,  DAMBORSKI, Jiri' ,  OPLUSTIL, Frantisek ,  JESENSKA', Andrea ,  NAGATA, Yuji

    IPC分类号： A62D3/00 ,  B09C1/10 ,  C02F3/34 ,  C02F11/00 ,  C02F11/02 ,  C02F101/36

    CPC分类号： A62D3/02 ,  A62D2101/02 ,  C02F3/34 ,  C02F11/004 ,  C02F11/02 ,  C02F2101/36 ,  C02F2209/06

    摘要： The method of detoxification of yperite - bis(2-chloroethyl) sulfide - by the use of a haloalkane dehalogenases or their compositions, the method of preparation of dehalogenationating enzymes and of decontamination compositions which contains at least one wild type and/or modified haloalkane dehalogenase (EC 3.8.1.5) as an chemically active component. The preferred dehalogenases are LJnB from Sphingomonas paucimobilis UT26, DhaA from Rhodococcus rodochrous NCIMB 13064, DmbA from Mycobacterium bovis 5033/66. Decontamination is utilizable for detoxification of yperite from the surfaces of instrumentality, constructional objects, human or animal skin and elements of environment by the treatment of yperite with the detoxification composition according the invention at +10°C to +70°C, preferably at about +40°C and pH from 4 to 12.

    摘要翻译： 通过使用卤代烷烃脱卤素酶或它们的组合物来解毒赤铁矿 - 双（2-氯乙基）硫化物的方法，制备脱卤素酶的方法和包含至少一种野生型和/或经修饰的卤代烷烃脱卤素酶 （EC 3.8.1.5）作为化学活性成分。 优选的脱卤素酶是来自Sphingomonas paucimobilis UT26的LJnB，来自棒状红球菌NCIMB 13064的DhaA，来自牛分枝杆菌5033/66的DmbA。 通过在+ 10℃至+ 70℃下用本发明的解毒组合物处理赤铁矿，去污可用于从工具，建筑对象，人或动物皮肤和环境要素的表面解毒赤铁矿，优选在约 + 40°C，pH值从4到12。