公开(公告)号：EP2460890A1

公开(公告)日：2012-06-06

申请号：EP10193362.0

申请日：2010-12-01

申请人： Max-Delbrück-Centrum für Molekulare Medizin (MDC)

发明人： Bader, Michael ,  Öczelik, Cemil ,  Mühlstedt, Silke

IPC分类号： C12Q1/68

CPC分类号： C12Q1/6883 ,  C12Q2600/158 ,  G01N33/6893 ,  G01N2800/32

摘要： The present invention relates to the gene Gpnmb and its use as a genetic marker in the incidence of cardiovascular conditions and cardiac diseases, such as complications derived from myocardial infarction. Gpnmb provides a valuable tool both for diagnostic as well as therapeutic approaches, in order to treat or prevent cardiovascular conditions and cardiac diseases, in particular complications derived from myocardial infarction.

摘要翻译： 本发明涉及基因Gpnmb及其在心血管疾病和心脏病发病中的遗传标记物的用途，例如由心肌梗死引起的并发症。 Gpnmb为诊断和治疗方法提供了宝贵的工具，以治疗或预防心血管疾病和心脏疾病，特别是由心肌梗死引起的并发症。