专利检索 ap:("Max-Delbrück-Centrum für Molekulare Medizin in der Helmholtz-Gemeinschaft" OR "Charité - Universitätsmedizin Berlin") AND inv:"THIEDE, Katerina" 第 1 页

1.

发明公开
T-CELL RECEPTORS SPECIFIC FOR HEPATITIS C VIRUS PEPTIDES 审中-公开

公开(公告)号：EP4067371A1

公开(公告)日：2022-10-05

申请号：EP21166438.8

申请日：2021-03-31

申请人： Max-Delbrück-Centrum für Molekulare Medizin in der Helmholtz-Gemeinschaft , Charité - Universitätsmedizin Berlin

发明人： BLANKENSTEIN, Thomas , THIEDE, Katerina , WILLIMSKY, Gerald

IPC分类号： C07K14/435

摘要： The invention is based on antigen binding proteins (ABPs) such as T-cell receptors (TCR) expressed on T-cells, which have a specificity to bind to MHC presented Hepatitis C Virus peptides. Provided are isolated ABPs as well as genetic constructs expressing the ABPs, recombinant host cells harboring the ABP of the invention and methods for producing such ABPs and host cells. Moreover, provided are medical applications involving the TCR of the invention, for example in context of an adoptive T-cell therapy.