专利检索 ap:("Max-Planck-Gesellschaft zur Förderung der Wissenschaften e.V.") AND inv:"WU, Peng" 第 1 页

1.

发明公开
RNA-BINDING MOLECULES WITH A SMALL CORE SCAFFOLD (R-SCORE) AND USES THEREOF 审中-公开

公开(公告)号：EP4357343A1

公开(公告)日：2024-04-24

申请号：EP22202598.3

申请日：2022-10-19

申请人： Max-Planck-Gesellschaft zur Förderung der Wissenschaften e.V.

发明人： WU, Peng , JIANG, Mao , LIU, Yang , BORGELT, Lydia

IPC分类号： C07D417/04 , C07D401/04 , C07D401/12 , C07D403/14 , C07D413/14 , C07D417/14 , C07D495/04 , A61K31/397 , A61P35/00 , A61K31/428 , A61K31/4439 , A61K31/506 , A61K31/496 , A61K31/4365 , C07D401/14

CPC分类号： C07D417/04 , C07D495/04 , C07D401/12 , C07D413/14 , C07D403/14 , C07D401/14 , C07D401/04 , C07D417/14 , A61P35/00

摘要： The present invention relates to novel RNA-binding azetidine compounds of general formula (I) and stereoisomeric forms, hydrates, solvates and pharmaceutically acceptable salts thereof, as well as pharmaceutical compositions containing said azetidine compound together with at least one pharmaceutically acceptable carrier, excipient and/or diluent. Said azetidine compounds are particularly useful for the treatment and/or prophylaxis of diseases caused by and/or associated with microRNA expression or microRNA misexpression, particularly cancer, tumor, virus infections, immune-related diseases, inflammatory diseases, diabetes, cardiovascular diseases, metabolic diseases, and neurodegenerative diseases.