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公开(公告)号:EP2751136B1
公开(公告)日:2017-10-18
申请号:EP12828994.9
申请日:2012-08-21
CPC分类号: C07K14/58 , A61K38/00 , A61K38/1709 , A61K38/2242 , C07K7/08 , C07K14/47
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公开(公告)号:EP2751136A1
公开(公告)日:2014-07-09
申请号:EP12828994.9
申请日:2012-08-21
CPC分类号: C07K14/58 , A61K38/00 , A61K38/1709 , A61K38/2242 , C07K7/08 , C07K14/47
摘要: This document provides methods and materials related to natriuretic polypeptides and the use of natriuretic polypeptides to treat cardiovascular and/or renal conditions. For example, chimeric polypeptides having at least one amino acid segment (e.g., N-terminus tail, ring structure, C-terminus tail, or a combination thereof) of a natriuretic peptide (e.g., ANP, BNP, CNP, URO, or DNP) and an amino acid segment of an angiotensin polypeptide (e.g., Ang-(1-7)) are provided.
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