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    Methods of preparing non-alcohol bioactive essential oil mouth rinses
    1.
    发明公开
    Methods of preparing non-alcohol bioactive essential oil mouth rinses 有权
    Verfahren zur Herstellung nichtalkoholischerMundspülungenmit bioaktivenätherischenÖlen

    公开(公告)号：EP2401999A3

    公开(公告)日：2015-08-05

    申请号：EP11172215.3

    申请日：2011-06-30

    申请人： McNeil-PPC, Inc.

    发明人： Mordas, Carolyn, J. ,  Queiroz, Daniel R. ,  Tsai, Patrick B.

    IPC分类号： A61K8/34 ,  A61K8/368 ,  A61K8/37 ,  A61K8/39 ,  A61K8/46 ,  A61K8/90 ,  A61Q11/00

    CPC分类号： A61K8/345 ,  A61K8/34 ,  A61K8/347 ,  A61K8/368 ,  A61K8/37 ,  A61K8/39 ,  A61K8/463 ,  A61K8/4973 ,  A61K8/498 ,  A61K8/86 ,  A61K8/90 ,  A61K8/922 ,  A61K2800/30 ,  A61K2800/74 ,  A61K2800/92 ,  A61Q11/00

    摘要： The invention relates generally to liquids such as mouth rinses for the prevention and elimination of bad breath as well as for the reduction of oral microorganisms responsible for the development of dental plaque and tooth decay. In particular, the present invention relates to a method of preparing non-alcohol or reduced alcohol mouth rinses effective at preventing the above-mentioned problems.
    The liquid composition is made by a method comprising the steps of:
    a.) preparing a first premix composition comprising:
    i. a first oil or oily component;
    ii. optionally, a first polyol solvent,
    iii. optionally, a flavour;
    b.) preparing a second premix composition comprising:
    i. a second oil or oily component having a degree of hydrophobicity less than the degree of hydrophobicity of the first oil or oily component; and
    ii. a second polyol solvent;
    c.) preparing a third premix composition comprising:
    i. at least one surfactant; and
    ii. an aqueous phase comprising water;
    d.) adding the first premix to the third premix;
    e.) mixing the composition of step d.) until uniform and homogeneous; and
    f.) adding the second premix to the composition of step e.) and mixing until uniform and homogeneous.

    摘要翻译： 本发明一般涉及用于预防和消除口臭以及减少负责牙菌斑和蛀牙发展的口腔微生物的液体如漱口水。 特别地，本发明涉及一种制备有效防止上述问题的非酒精或还原酒精漱口剂的方法。 液体组合物通过包括以下步骤的方法制备：a）制备第一预混物组合物，其包含： 第一种油或油性成分; II。 任选地，第一多元醇溶剂，iii。 任选地，一种风味; b。）制备第二预混物组合物，其包含： 疏水性小于第一油或油性成分疏水度的第二油或油性成分; 和ii。 第二多元醇溶剂; c。）制备第三种预混组合物，其包含： 至少一种表面活性剂; 和ii。 包含水的水相; d。）将第一预混物加入到第三预混物中; e）将步骤d。）的组合物混合直至均匀均匀; 和f）将第二预混物加入到步骤e。）的组合物中并混合直到均匀均匀。