公开(公告)号：EP2840081A1

公开(公告)日：2015-02-25

申请号：EP13778232.2

申请日：2013-04-19

申请人： Medicinal Bioconvergence Research Center

发明人： KIM, Sunghoon ,  LEE, Hee Sook ,  OH, Young Sun ,  KIM, Dae Gyu

IPC分类号： C07D213/75 ,  C07D215/38 ,  A61K31/435 ,  A61P35/00

CPC分类号： C07D215/38 ,  A61K31/435 ,  C07D213/75

摘要： The present invention relates to the use of a novel aminopyridine derivative to prevent or treat cancer, and more particularly to a carcinostatic composition including a compound of Formula 1 or a derivative thereof as an active principle. The compound of the present invention degrades the activation of AIMP2-D7C2 targeted by a novel anticancer drug so as to effectively in-duce destruction of cancer cells, thus effecting prevention and treatment of cancer. Therefore the compound of the present invention can be used to prevent and treat cancer.

摘要翻译： 本发明涉及新型氨基吡啶衍生物用于预防或治疗癌症的用途，更具体地涉及包含式1化合物或其衍生物作为活性成分的制癌组合物。 本发明的化合物降低了由新型抗癌药物靶向的AIMP2-D7C2的活化，有效地降低了癌细胞的破坏，从而进行了癌症的预防和治疗。 因此，本发明的化合物可用于预防和治疗癌症。