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公开(公告)号：EP2704795B1
公开(公告)日：2015-01-14
申请号：EP12722975.5
申请日：2012-05-02
申请人： Medtronic, Inc.
CPC分类号： A61N1/3702 , A61B5/0215 , A61B5/686 , A61B5/7207 , A61B5/7239 , A61N1/36564
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公开(公告)号：EP1572293B1
公开(公告)日：2012-02-29
申请号：EP03779260.3
申请日：2003-10-27
申请人： Medtronic, Inc.
CPC分类号： A61N1/3601 , A61N1/365 , A61N2001/0585
摘要： The invention is directed to an implantable medical device that stimulates a nerve associated with respiration. The nerve may, for example be a phrenic nerve, and the stimulation may cause a diaphragm of the patient to contract. The implantable medical device receives a signal that indicates a need for increased cardiac output and stimulates the nerve in response to the signal. The implantable medical device may receive such a signal by, for example, detecting a ventricular tachyarrhythmia, sensing a pressure that indicates a need for increased cardiac output, or receiving a signal from a patient via a patient activator. Stimulation of the nerve may increase cardiac output of a beating or defibrillating heart
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3.发明公开IMPLANTABLE MEDICAL DEVICE FOR TREATING CARDIAC MECHANICAL DYSFUNCTION BY ELECTRICAL STIMULATION 审中-公开植入式医疗设备，机械心脏功能障碍的电刺激治疗的
公开(公告)号：EP1429839A2
公开(公告)日：2004-06-23
申请号：EP02797838.6
申请日：2002-08-28
申请人： Medtronic, Inc.
CPC分类号： A61N1/3956 , A61N1/36014 , A61N1/36114 , A61N1/3625 , A61N1/3627 , A61N1/36585 , A61N1/3706
摘要： The above-described methods and apparatus are believed to be of particular benefit for patients suffering heart failure including cardiac dysfunction, chronic HF, and the like and all variants as described herein and including those known to those of skill in the art to which the invention is directed. It will understood that the present invention offers the possibility of monitoring and therapy of a wide variety of acute and chronic cardiac dysfunctions. The current invention provides systems and methods for delivering therapy for cardiac hemodynamic dysfunction.
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公开(公告)号：EP1713538A1
公开(公告)日：2006-10-25
申请号：EP04812793.0
申请日：2004-12-01
申请人： MEDTRONIC, INC.
发明人： HAVEL, William, J.
IPC分类号： A61N1/38
CPC分类号： A61N1/3962 , A61N1/3937
摘要： A method and apparatus for actively determining a coupling interval corresponding to a cardiac vulnerable zone associated with a therapy of an implantable medical device that includes a timing and control unit delivering, via electrodes of a plurality of electrodes, a first pulse train and a first pulse signal at a predetermined time interval from delivery of a last pulse of the first pulse train. A sensor determines an evoked response corresponding to the first pulse signal, and a microprocessor compares the evoked response to a prior determined evoked response and sets the coupling interval equal to the predetermined time interval in response to the latency of the evoked response having increased by a first predetermined amount, and reduces the predetermined time interval by a second predetermined amount in response to the latency of the evoked response not having increased by the first predetermined amount.
摘要翻译： 一种用于主动确定对应于与可植入医疗设备的治疗相关联的心脏脆弱区的耦合间隔的方法和设备，所述方法和设备包括定时和控制单元，其经由多个电极的电极递送第一脉冲串和第一脉冲 信号从传递第一脉冲串的最后一个脉冲起的预定时间间隔。 传感器确定对应于第一脉冲信号的诱发响应，并且微处理器将诱发响应与先前确定的诱发响应进行比较，并且响应于诱发响应的等待时间增加a，将耦合间隔设置为等于预定时间间隔 第一预定量，并且响应于诱发响应的延迟未增加第一预定量，将预定时间间隔减小第二预定量。
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公开(公告)号：EP1455897A2
公开(公告)日：2004-09-15
申请号：EP02804520.1
申请日：2002-12-03
申请人： Medtronic, Inc.
发明人： HAVEL, William, J. , DEGROOT, Paul, J. , SINNER, Thomas, W. , KUEHN, Kevin , KEMMETMUELLER, Gary , WOLD, Warren, W.
IPC分类号： A61N1/39
CPC分类号： A61N1/3906 , A61N1/3912 , A61N1/3937
摘要： The present invention outlines structures and methods for delivering a controllable amount of energy to a patient by automatically compensating for the load impedance detected by an implantable-cardioverter defibrillator (ICD). The invention employs high speed, switching power converter technology for the efficient generation of high energy, arbitrary waveforms. Unlike a linear amplifier, switching power converters deliver high-energy waveforms with an efficiency that is independent of the size and amplitude of the desired waveform. An ICD that uses a switching power converter to deliver the desired energy to the patient stores the energy to be delivered in a storage capacitor. The converter then transforms this energy into an arbitrarily shaped output voltage-controlled or current-controlled waveform by switching the storage capacitor in and out of the output circuit at a high rate of speed. Preferably, the waveform comprises a ramp-type waveform.
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公开(公告)号：EP1713538B1
公开(公告)日：2010-07-07
申请号：EP04812793.0
申请日：2004-12-01
申请人： Medtronic, Inc.
发明人： HAVEL, William, J.
IPC分类号： A61N1/38
CPC分类号： A61N1/3962 , A61N1/3937
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7.发明公开IMPLANTABLE SUBCUTANEOUS MEDICAL DEVICE PROVIDING POST-EXTRA-SYSTOLIC POTENTIATION THERAPY 审中-公开提供术后体外强化治疗的可植入式皮下注射医疗装置
公开(公告)号：EP1986736A1
公开(公告)日：2008-11-05
申请号：EP07710285.3
申请日：2007-01-24
申请人： MEDTRONIC, INC.
CPC分类号： A61N1/36514 , A61N1/36528 , A61N1/36542 , A61N1/3702 , A61N1/3962
摘要： An ICD system adapted for subcutaneous implantation, the system comprising: a pair of electrodes adapted to deliver electrical stimulation to a heart; a set of low polarization electrodes for sensing a response to electrical potentiation pulses delivered from the first pair of electrodes; and a counter for logging a duration of fast VT and VF between high voltage shocks that restore normal sinus rhythm to the heart, the shocks delivered by the first pair of electrodes.
摘要翻译： 一种适用于皮下植入的ICD系统，该系统包括：一对电极，适于向心脏输送电刺激; 一组低极化电极，用于感测对从第一对电极传递的电增强脉冲的响应; 以及用于在高电压冲击之间记录快速VT和VF持续时间的计数器，所述高电压冲击恢复正常窦性心律至第一对电极所传递的冲击。
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公开(公告)号：EP2704795A1
公开(公告)日：2014-03-12
申请号：EP12722975.5
申请日：2012-05-02
申请人： Medtronic, Inc.
CPC分类号： A61N1/3702 , A61B5/0215 , A61B5/686 , A61B5/7207 , A61B5/7239 , A61N1/36564
摘要： An example system may include at least one pressure sensor configured to measure a cardiovascular pressure signal and another medical device configured to measure an electrical depolarization signal of the heart. The system determines a plurality of cardiovascular pressure metrics based on the measured cardiovascular pressure signal, including at least one cardiovascular pressure metric indicative of a timing of at least one cardiac pulse. The system also determines a metric indicative of a timing of at least one heart depolarization within the measured electrical depolarization signal. The system compares the timing of the at least one cardiac pulse to the timing of the at least one depolarization, and determines whether to discard the plurality of cardiovascular pressure metrics based on whether the timings substantially agree.
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9.发明授权APPARATUS FOR VALIDATING A PACING TRAIN ASSOCIATED WITH T-SHOCK DELIVERY 有权设备进行验证起搏列车的均与T-SHOCK管理方面
公开(公告)号：EP1899008B1
公开(公告)日：2011-05-18
申请号：EP06750734.3
申请日：2006-04-17
摘要： A method and apparatus for validating cardiac pacing pulse train preceding a T- shock. Validation of the pacing pulse train includes verifying capture of at least the last pacing pulse of the pulse train and verifying that intrinsic ventricular events are not sensed during a pacing train interval that includes at least the interval between the last pacing pulse and a scheduled T-shock delivery. Capture verification may include sensing an event during an ER (evoced response) sensing window, morphological analysis of a sensed event, and analysis of the temporal relationship between sensed events occurring on different EGM sources. The scheduled T-shock is delivered in response to a valid pacing pulse train. A response to an invalid pacing pulse train may include any of an invalid pacing train notification, withholding a scheduled T-shock, extension of the pacing train, repeating the pacing train, or adjusting the pacing pulse train parameters.
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10.发明公开METHOD AND APPARATUS FOR VALIDATING A PACING TRAIN ASSOCIATED WITH T-SHOCK DELIVERY 有权设备进行验证起搏列车的均与T-SHOCK管理方面
公开(公告)号：EP1899008A1
公开(公告)日：2008-03-19
申请号：EP06750734.3
申请日：2006-04-17
申请人： MEDTRONIC, INC.
摘要： A method and apparatus for validating cardiac pacing pulse train preceding a T- shock. Validation of the pacing pulse train includes verifying capture of at least the last pacing pulse of the pulse train and verifying that intrinsic ventricular events are not sensed during a pacing train interval that includes at least the interval between the last pacing pulse and a scheduled T-shock delivery. Capture verification may include sensing an event during an ER (evoced response) sensing window, morphological analysis of a sensed event, and analysis of the temporal relationship between sensed events occurring on different EGM sources. The scheduled T-shock is delivered in response to a valid pacing pulse train. A response to an invalid pacing pulse train may include any of an invalid pacing train notification, withholding a scheduled T-shock, extension of the pacing train, repeating the pacing train, or adjusting the pacing pulse train parameters.
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