专利检索 ap:("Merck & Co., Inc.") AND inv:"LEBSACK, Alec, D." 第 1 页

1.

发明授权
VLA-4 ANTAGONISTS 有权
标题翻译： VLA-4拮抗剂

公开(公告)号：EP1781686B1

公开(公告)日：2009-05-06

申请号：EP05808535.8

申请日：2005-08-12

申请人： Merck & Co., Inc.

发明人： CHEN, Weichao , LEBSACK, Alec, D. , MUNOZ, Benito , VENKATRAMAN, Shankar , WANG, Bowei

IPC分类号： C07K5/078 , A61K38/05 , A61P11/06 , A61P19/02 , A61P25/28

CPC分类号： C07K5/06139 , C07K5/06191

摘要： Compounds of Formula (I) are antagonists of VLA-4, and as such are useful in the inhibition or prevention of cell adhesion and cell-adhesion mediated pathologies. These compounds may be formulated into pharmaceutical compositions and are suitable for use in the treatment of inflammatory bowel disease including ulcerative colitis and Crohn's disease, multiple sclerosis, asthma, and rheumatoid arthritis.

2.

发明公开
VLA-4 ANTAGONISTS 有权
标题翻译： VLA-4拮抗剂

公开(公告)号：EP1781686A2

公开(公告)日：2007-05-09

申请号：EP05808535.8

申请日：2005-08-12

申请人： Merck & Co., Inc.

发明人： CHEN, Weichao , LEBSACK, Alec, D. , MUNOZ, Benito , VENKATRAMAN, Shankar , WANG, Bowei

IPC分类号： C07K5/078 , A61K38/05 , A61P11/06 , A61P19/02 , A61P25/28

CPC分类号： C07K5/06139 , C07K5/06191

摘要： Compounds of Formula (I) are antagonists of VLA-4, and as such are useful in the inhibition or prevention of cell adhesion and cell-adhesion mediated pathologies. These compounds may be formulated into pharmaceutical compositions and are suitable for use in the treatment of inflammatory bowel disease including ulcerative colitis and Crohn’s disease, multiple sclerosis, asthma, and rheumatoid arthritis.